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6-Methylbenzimidazoleacetonitrile

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Identification
Molecular formula
C11H11N3
CAS number
86520-86-9
IUPAC name
2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile
State
State

At room temperature, 6-Methylbenzimidazoleacetonitrile is typically found in a solid state. It is stable under standard temperature and pressure conditions.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
363.70
Boiling point (Kelvin)
636.85
General information
Molecular weight
171.20g/mol
Molar mass
171.1970g/mol
Density
1.1600g/cm3
Appearence

The compound appears as a white to off-white crystalline solid. The solid form may be powdery in texture and is generally free-flowing. It may also have a faint characteristic odor typical of organic nitriles.

Comment on solubility

Solubility of 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile

The solubility of 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile can vary significantly based on the solvent used and the environmental conditions. Here are several key points to consider:

  • Solvent polarity: Generally, compounds with polar functional groups tend to dissolve better in polar solvents such as water and alcohols. However, the specific solubility of this compound has not been extensively documented.
  • Hydrophilicity vs. hydrophobicity: This compound's structure suggests a balance between hydrophobic (benzimidazole moiety) and hydrophilic (acetonitrile) characteristics, potentially leading to moderate solubility in a range of organic solvents.
  • Temperature effects: Increased temperature can often enhance solubility. Thus, heating the solvent might increase the dissolution of this compound.
  • Concentration examples: If available, empirical data regarding its solubility at specific concentrations in various solvents could greatly aid in understanding its behavior.

In conclusion, while comprehensive solubility data for 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile may be limited, establishing its solubility characteristics is crucial for its practical applications. Factors like solvent choice and temperature should be well considered. As always, empirical testing is the best approach to determine the solubility in specific conditions.

Interesting facts

Interesting Facts about 2-(6-Methyl-1H-benzimidazol-2-yl)acetonitrile

2-(6-Methyl-1H-benzimidazol-2-yl)acetonitrile is a fascinating compound in the realm of organic chemistry, particularly for its role in medicinal chemistry and its potential applications. Here are some intriguing points about this compound:

  • Structural Features: This compound belongs to the family of benzimidazole derivatives, known for their diverse biological activities. The presence of a methyl group attached to the benzimidazole ring adds to its unique chemical properties, influencing its reactivity and interaction with biological systems.
  • Biological Significance: Compounds containing the benzimidazole moiety have been explored for their medicinal properties. They often exhibit antifungal, antiviral, and anticancer activities, making them valuable in pharmaceutical research.
  • Synthetic Versatility: The synthesis of 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile can serve as a starting point for the creation of various derivatives. This versatility allows chemists to modify its structure to enhance desired properties or develop new applications.
  • Potential in Agrochemicals: Beyond medicinal applications, compounds like this one are being investigated for their effectiveness in agrochemical formulations. Their inherent bioactivity could lead to the development of novel pesticides or herbicides.
  • Research Frontiers: Current research is diving deep into the mechanisms of action of benzimidazole derivatives. Understanding these mechanisms may unlock new therapeutic pathways, making compounds like 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile an exciting field of study.

In summary, as we explore 2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile, we uncover a compound that is not only structurally intriguing but also rich with potential applications in both medicinal and agricultural fields. The ongoing research in this area makes it a continuously evolving topic for scientists and students alike.

Synonyms
27099-22-5
2-BENZIMIDAZOLEACETONITRILE, 5-METHYL-
DTXSID00181560
RefChem:1074051
DTXCID40104051
6-Methyl-1H-benzimidazole-2-acetonitrile
2-(Cyanomethyl)-5-methylbenzimidazole
(5-methyl-1H-benzimidazol-2-yl)acetonitrile
2-(6-methyl-1H-benzimidazol-2-yl)acetonitrile
MFCD01658313
1H-Benzimidazole-2-acetonitrile,5-methyl-(9CI)
1H-Benzimidazole-2-acetonitrile, 5-methyl-
(6-methyl-1H-benzimidazol-2-yl)acetonitrile
2-(6-Methyl-1H-benzo[d]imidazol-2-yl)acetonitrile
2-(5-methylbenzimidazol-2-yl)ethanenitrile
5-Methyl-2-benzimidazoleacetonitrile
2-(5-methyl-1H-1,3-benzodiazol-2-yl)acetonitrile
SCHEMBL8985172
SCHEMBL8985181
SCHEMBL31516298
PDULDINSGIRDOX-UHFFFAOYSA-N
HMS1659A03
ALBB-024901
AC1435
MFCD00463035
SBB045302
STK319189
AKOS000274573
AKOS000399904
CS-12324
SY046471
DB-108144
ST4104216
CS-0318225
(5-Methyl-1H-benzoimidazol-2-yl)acetonitrile
AF-615/00097043