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Nipagin M

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Identification
Molecular formula
C12H11N7O3
CAS number
64169-18-0
IUPAC name
2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine
State
State

At room temperature, the compound is in a stable solid state. It is often stored in tightly sealed containers to avoid moisture uptake and degradation.

Melting point (Celsius)
263.00
Melting point (Kelvin)
536.15
Boiling point (Celsius)
443.00
Boiling point (Kelvin)
716.15
General information
Molecular weight
288.27g/mol
Molar mass
288.2720g/mol
Density
1.5367g/cm3
Appearence

The compound is typically found as a white to light yellow crystalline powder. It is often described as having a faint characteristic odor. The crystalline nature contributes to its fine particulate appearance under a microscope.

Comment on solubility

Solubility of 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine

Understanding the solubility of 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine is crucial for its applications in various chemical processes and pharmaceutical formulations. This compound, with its complex structure, exhibits particular solubility characteristics that can be influenced by several factors:

  • Polarity: The presence of various functional groups, such as the guanidine and nitro groups, can affect the polarity of the molecule. This often leads to increased solubility in polar solvents like water, whereas non-polar solvents may not dissolve the compound as effectively.
  • Hydrogen bonding: The ability of this compound to engage in hydrogen bonding can result in enhanced solubility in polar environments. The guanidine functional group can form hydrogen bonds with water, facilitating its dissolution.
  • pH sensitivity: The solubility of this guanidine derivative may vary with pH. In acidic or basic conditions, the charges on the molecule can change, potentially affecting its overall solubility.

In summary, the solubility of 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine can be described as:

  1. Generally more soluble in polar solvents due to its structural features.
  2. Exhibiting varying degrees of solubility under different pH conditions.
  3. Showcasing potential for increased solubility through hydrogen bonding interactions.

These factors highlight the necessity for careful consideration when evaluating the solubility of this compound in practical applications.

Interesting facts

Interesting Facts about 2-(6-Methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine

This compound is a fascinating member of the guanidine family, which has garnered attention in various fields such as medicinal chemistry and organic synthesis. Known for its unique structure, it combines a pyrimidinone ring with a nitrophenyl group, highlighting its potential versatility.

Key Features

  • Biological Activity: Compounds related to guanidine often exhibit profound biological activity, ranging from antibacterial to antifungal properties, making this compound a candidate for pharmaceutical research.
  • Synthetic Relevance: The synthesis of this compound can involve various interesting chemical reactions, making it a suitable subject for organic chemists aiming to develop methodologies in compound synthesis.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the guanidine core affect its activity can empower researchers to design more effective compounds with targeted biological actions.

Chemical Applications

Furthermore, this compound's unique functional groups hint at its potential use in:

  • As a building block in organic synthesis
  • Investigating new therapeutic agents
  • Studying the interaction mechanisms of drugs at a molecular level

Quote to Consider

As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." This compound could represent a fascinating idea in the realm of chemical research—one that might lead to significant advancements in healthcare or material sciences.

In conclusion, 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-(4-nitrophenyl)guanidine stands as a prime example of how diverse chemical structures can hold promise for future innovations across different scientific landscapes.