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Acyclovir

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Identification
Molecular formula
C8H11ClN6O
CAS number
59277-89-3
IUPAC name
2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine
State
State

Acyclovir is solid at room temperature. It typically comes in the form of a crystalline powder, suitable for various pharmaceutical formulations.

Melting point (Celsius)
256.50
Melting point (Kelvin)
529.65
Boiling point (Celsius)
507.00
Boiling point (Kelvin)
780.15
General information
Molecular weight
225.21g/mol
Molar mass
225.2090g/mol
Density
1.4780g/cm3
Appearence

Acyclovir is commonly found as a white crystalline powder. It is odorless and can be characterized by its crystalline appearance. The powder is slightly hygroscopic.

Comment on solubility

Solubility Characteristics of 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine

This organic compound, 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine, exhibits specific solubility properties that are influenced by its chemical structure. The solubility of a compound is often determined by several factors, including:

  • Polarity: The presence of polar functional groups in the molecular structure can significantly enhance solubility in polar solvents.
  • Molecular Weight: Generally, lower molecular weight compounds tend to be more soluble than their heavier counterparts.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvents can increase solubility in aqueous environments.
  • pH of the Solution: The solubility can change with pH, particularly for compounds containing basic or acidic functional groups.

In the case of 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine, the diverse functional groups suggest that it may show moderate solubility in various organic solvents. However, it may exhibit limited solubility in water, again depending on the specific interactions with the solvent. As noted in the literature, this compound is likely to be:
“more soluble in polar solvents than in non-polar ones”.

When exploring its applications or conducting experiments, understanding its solubility can be crucial for selecting the right solvents for extraction, formulation, or further chemical reactions.

Interesting facts

Interesting Facts about 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine

2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine is a fascinating compound that belongs to the class of guanidine derivatives. This compound showcases a unique combination of structural features that contribute to its potential biological activities. Here are some intriguing points about this compound:

  • Pharmaceutical Relevance: Compounds in the guanidine class are often investigated for their various pharmacological properties. They have been reported to exhibit activities such as antioxidative, anti-inflammatory, and even antidiabetic effects.
  • Structural Complexity: The pyrimidine ring present in this compound contributes to its heterocyclic nature, enhancing its biological interaction possibilities. This complexity can lead to intriguing mechanisms of action in biological systems.
  • Synthetic Chemistry: The synthesis of such multi-functionalized compounds often requires advanced synthetic techniques. Chemists may use strategies such as multicomponent reactions to efficiently construct these intricate structures.
  • Research Potential: Due to its unique structure, researchers are continuously exploring the potential implications of this compound in drug design and medicinal chemistry. It is an excellent example of how slight modifications in chemical structure can lead to differences in biological activity.
  • Real-world Applications: The study of guanidine derivatives like this one could pave the way for the development of new therapeutic agents, especially in treating chronic diseases.

In summary, 2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)-1-phenyl-guanidine embodies the vital relationship between chemistry and medicine. As chemists continue to delve into its properties, it’s essential to appreciate how such compounds can lead to real-world benefits, showcasing the power of innovation in the field of chemical science.