Skip to main content

Clonazepam

ADVERTISEMENT
Identification
Molecular formula
C15H10ClN3O3
CAS number
1622-62-4
IUPAC name
2-(6,11-dihydrobenzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, clonazepam is typically in a solid state. It is often supplied in tablet form or as an oral solution for medical use.

Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
315.73g/mol
Molar mass
315.7250g/mol
Density
1.3000g/cm3
Appearence

Clonazepam typically appears as a white to off-white crystalline powder. It is generally odorless and has a bitter taste. The compound is highly soluble in chloroform and only sparingly soluble in water.

Comment on solubility

Solubility of 2-(6,11-dihydrobenzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility of the compound 2-(6,11-dihydrobenzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate can be considered under several factors influenced by its molecular structure. Here are some key insights:

  • Polar versus Nonpolar Characteristics: The presence of the dimethyl-ammonium group suggests a level of polarity due to the quaternary nitrogen, which generally enhances solubility in polar solvents such as water.
  • Functional Groups: The 4-hydroxy-4-oxo-but-2-enoate moiety may contribute to hydrogen bonding, increasing solubility in aqueous environments.
  • Solvent Compatibility: Solubility trends suggest that this compound may dissolve well in solvents like methanol or ethanol that can accommodate its polar and nonpolar regions.
  • Concentration Effects: At certain concentrations, the compound might exhibit enhanced solubility due to possible self-association or structural conformations that optimize interaction with the solvent.

In conclusion, while definitive solubility data may vary depending on environmental conditions, it can be summarized that this compound is likely to be soluble in polar solvents, owing to its unique structural features and functional groups. For practical applications, testing in specific solvents would provide more accurate insights into its solubility profile.

Interesting facts

Interesting Facts About 2-(6,11-Dihydrobenzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound is a fascinating example of the intricate world of organic chemistry, particularly within the realm of pharmacology and medicinal chemistry. Its unique structure and functional groups contribute to a variety of biological activities. Here are some intriguing points to consider:

  • Dual Functionality: This compound features both a benzodiazepine moiety, known for its anxiolytic and sedative properties, and a hydroxy-2-en-4-one component, which adds potential for reactivity and biological interactions.
  • Potential Therapeutic Uses: The benzodiazepine component is typically associated with drugs that treat anxiety, insomnia, and seizure disorders, while the enone group suggests reactivity that could lead to the development of novel therapeutic agents.
  • Mechanistic Insights: The presence of the dimethylammonium group indicates that the compound may exhibit ionic character, influencing its interaction with biological membranes and receptors.
  • Synthetic Pathways: The synthesis of such complex compounds often involves several reaction steps and techniques, such as cyclization and functionalization, highlighting the creativity and problem-solving skills required in organic synthesis.
  • Research Potential: Compounds like this one are of great interest in the field of drug design, as they can serve as lead compounds for further modification and optimization in the pursuit of enhanced efficacy and safety profiles.

In summary, the compound not only exemplifies the rich tapestry of chemical interactions and biological implications but also presents a wonderful opportunity for research and development in medicinal chemistry. As scientists continue to explore its properties, we can anticipate exciting advancements influenced by such innovative molecular designs.