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Diclofenac

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Identification
Molecular formula
C14H10Cl2NO2
CAS number
15307-79-6
IUPAC name
2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid
State
State

Solid

At room temperature, diclofenac is in a solid state. It is typically supplied in a crystalline powder form, and often processed into tablets or gel formulations for medicinal use.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
296.15g/mol
Molar mass
296.1480g/mol
Density
1.2300g/cm3
Appearence

Diclofenac appears as a white to slightly yellow crystalline powder. The compound may also exhibit a faint or mild odor, and it is typically not soluble in water, but soluble in organic solvents. The crystals can vary slightly in color but usually maintain a consistent, uniform appearance.

Comment on solubility

Solubility of 2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid

The solubility of 2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid can be influenced by a variety of factors. Here are some key points to consider:

  • Polarity: This compound has both hydrophilic and hydrophobic regions, which can affect its solubility in different solvents.
  • Solvent Choice: Generally, compounds with similar polarities tend to dissolve well together. Therefore, it may have better solubility in organic solvents compared to water.
  • Temperature Effects: Increasing temperature often enhances solubility for many compounds. It could be beneficial to examine how this compound reacts to varying temperatures to determine solubility changes.
  • pH Influence: Given that it is an acid, the solubility may vary with pH, potentially increasing in more basic environments where it can ionize.

In summary, while 2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid has complex solubility characteristics, understanding its solubility profile requires careful examination of the factors mentioned above. As with many compounds, testing under various conditions is essential for a complete assessment.

Interesting facts

Interesting Facts about 2-(6,7-Dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic Acid

This intriguing compound, 2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid, possesses a unique structural configuration that significantly influences its chemical behavior and potential applications. Here are some fascinating aspects:

  • Complex Structure: The compound features a multidimensional structure that includes an indan-5-yl skeleton and multiple chiral centers, raising interest for synthetic chemists in the field of asymmetric synthesis.
  • Chlorine Substitution: The presence of dichloro groups (6,7-dichloro) can impart unique electronic characteristics to the molecule, potentially enhancing its reactivity and making it a candidate for various chemical reactions.
  • Biological Relevance: Compounds with similar frameworks are often investigated for their pharmacological properties, suggesting potential roles in medicinal chemistry as therapeutic agents.
  • Oxyacetic Acid Derivative: As an oxyacetic acid, this molecule could have functional applications in the fields of agrochemicals or as intermediates in the synthesis of more complex organic compounds.
  • Environmental Impact: The study of halogenated compounds like this one is essential in understanding their environmental persistence and toxicity, guiding regulatory approaches in chemistry and ecology.

In conclusion, the rich structural nuances and potential applications of 2-(6,7-dichloro-2-cyclopentyl-1-oxo-indan-5-yl)oxyacetic acid make it a compelling subject of study for chemists aiming to explore new compounds with innovative uses. As we continue to investigate its properties and behaviors, we unlock further understanding of its implications in various scientific fields.

Synonyms
BRN 1891685
2-Cyclopentyl-6,7-dichloro-1-oxo-5-indanyloxyacetic acid
27366-52-5
ACETIC ACID, 2-CYCLOPENTYL-6,7-DICHLORO-1-OXO-5-INDANYLOXY-
RefChem:316517
CHEMBL404814
SCHEMBL11112986
DTXSID10950067
[(6,7-Dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]acetic acid