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Etodolac

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Identification
Molecular formula
C17H21Cl2NO3
CAS number
41340-25-4
IUPAC name
2-(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yl)oxyacetic acid
State
State
Etodolac is typically a solid at room temperature. It is usually handled in a powdered form for pharmaceutical applications.
Melting point (Celsius)
145.50
Melting point (Kelvin)
418.65
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
287.72g/mol
Molar mass
287.7180g/mol
Density
1.4700g/cm3
Appearence

Etodolac appears as a white crystalline powder. It is practically insoluble in water and tends to have a slight odor.

Comment on solubility

Solubility of 2-(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yl)oxyacetic acid

The solubility of 2-(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yl)oxyacetic acid (C17H21Cl2NO3) can be influenced by several factors, including its chemical structure and interactions with solvents. Understanding its solubility is essential for various applications in chemical formulations.

Factors Affecting Solubility

  • Polarity: The presence of the carboxylic acid group may enhance solubility in polar solvents like water.
  • Functional Groups: The dichloro and alkyl groups can affect the molecule's overall hydrophobic character.
  • Temperature: Solubility can vary significantly with temperature changes.

Generally, compounds similar to this one exhibit the following solubility behavior:

  • Soluble: In polar solvents (e.g., water, ethanol).
  • Insoluble: In non-polar solvents (e.g., hexane, toluene).

It is worth noting that, as with many organic compounds, solubility can dramatically impact bioavailability and efficacy in practical applications. Therefore, one must perform appropriate testing to determine the precise solubility characteristics in various contexts.

In conclusion, the solubility of C17H21Cl2NO3 is an important aspect to consider for its usage in pharmaceuticals, agrochemicals, and other chemical products, emphasizing the need for thorough investigation.

Interesting facts

Interesting Facts about 2-(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yl)oxyacetic Acid

This compound, known for its complex structure, presents intriguing properties and potential applications that are captivating to both chemists and researchers. Here are some key points that highlight its significance:

  • Diverse Functional Group: The presence of the oxyacetic acid component suggests potential for various chemical reactions, making it a versatile compound in synthetic chemistry.
  • Chlorine Substitution: The dichloro substitution can enhance biological activity, leading to interesting pharmacological properties, which merit further investigation.
  • Indan Framework: This compound boasts an indan structure, a scaffold commonly found in numerous natural products and pharmaceuticals, hinting at its utility in drug development.
  • Potential Biological Activity: Compounds similar to this have been explored for their herbicidal and medicinal effects, underscoring the importance of its study in agrochemicals and pharmaceuticals.
  • Synthesis Challenges: The complex structure may pose challenges in synthesis, making it a valuable subject of study in advanced organic chemistry and synthetic methodologies.

As a scientist or student exploring the vast landscape of organic compounds, studying 2-(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-indan-5-yl)oxyacetic acid opens doors to creativity and innovation. It serves as a promising example of how chemical modifications can lead to novel pathways in research and application.

In the words of a prominent chemist, "Chemistry is the art of transformation. Each compound is a canvas waiting for its artist." This compound truly exemplifies that philosophy!

Synonyms
IAA-94
53108-00-2
Indanyloxyacetic acid 94
54197-05-6
MK 473
MK-473
(Rac)-Methylindazone
[(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-2,3-dihydro-1h-inden-5-yl)oxy]acetic acid
54197-31-8
2-Cyclopentyl-6,7-dichloro-2-methyl-1-oxo-5-indanyloxyacetic acid
2-((6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetic acid
2-[(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-3H-inden-5-yl)oxy]acetic acid
2-[(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]acetic acid
R(+)-IAA-94
BRN 1893792
MFCD01672016
S-(-)-Methylindazone
CHEMBL79956
SCHEMBL460721
GTPL4217
DTXSID20969160
RNOJGTHBMJBOSP-UHFFFAOYSA-N
BCP32701
BCP32714
HY-12693A
[(6,7-dichloro-2-cyclopentyl-2-methyl-1-oxo-3H-inden-5-yl)oxy]acetic acid
ACETIC ACID, 2-CYCLOPENTYL-6,7-DICHLORO-2-METHYL-1-OXO-5-INDANYLOXY-
AKOS027338005
Acetic acid,[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)oxy]-
DA-48812
DB-217287
CS-0012303
F50593
Q27078010
(1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid
(+)[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)oxy]acetic acid
([6,7-dichloro-2-cyclo-pentyl-2,3-dihydro-2-methyl-1-oxo-1h-inden-5-yl)oxy] acetic acid
(+) [(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)-oxy]acetic acid
(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo- 1H-inden-5-yl)oxy]acetic acid
(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1-H-inden-5-yl)oxy]acetic acid
(+)-[(6,7-dichloro-2-cyclopentyl-2,3-dihydro-2-methyl-1-oxo-1H-inden-5-yl)oxy]acetic acid