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Nebularine

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Identification
Molecular formula
C10H13N5O4
CAS number
443-72-1
IUPAC name
2-(7-aminoimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
State
State

At room temperature, Nebularine is generally found in a solid state. It is stable under normal conditions and is often stored in a dry and cool place.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
545.00
Boiling point (Kelvin)
818.15
General information
Molecular weight
281.24g/mol
Molar mass
281.2630g/mol
Density
2.1000g/cm3
Appearence

Nebularine typically appears as a white or off-white solid in its pure form. It is often available as a crystalline powder.

Comment on solubility

Solubility of 2-(7-aminoimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

The solubility of the compound C10H13N5O4, specifically 2-(7-aminoimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, can be quite intriguing due to its unique structure that incorporates both hydrophilic and hydrophobic components.

When evaluating solubility, consider the following factors:

  • Polarity: This compound contains multiple functional groups, such as amines and hydroxyls, which can enhance its polarity, often leading to higher solubility in polar solvents like water.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups suggests the capability of forming hydrogen bonds with solvent molecules, which may increase aqueous solubility.
  • Hydrophobic Regions: Conversely, the imidazo compounds may contribute to hydrophobic characteristics that could limit solubility in certain environments.

In general, compounds with various functional groups can exhibit a range of solubility behaviors. As a result:

  • Solubility in water is anticipated to be moderate to high due to the hydroxyl and amino groups.
  • Solubility in organic solvents may vary, particularly if hydrophobic interactions dominate.

Ultimately, it is essential to conduct experimental investigations to determine the solubility under varying conditions, as theoretical predictions can only provide a guideline. In summary, while there are various factors at play, this compound's unique structure points to an interesting solubility profile that warrants further exploration.

Interesting facts

Exploring 2-(7-aminoimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This intriguing compound, commonly referred to by its structural name, exhibits a diverse range of chemical characteristics and potential applications in the field of medicinal chemistry. Here are some interesting insights:

  • Pharmacological Potential: Due to its unique structure, this compound has garnered attention for its possible roles in drug development and therapeutic applications. The presence of the imidazo[4,5-b]pyridine moiety suggests activity against various biological targets, including enzymes and receptors.
  • Hydroxymethyl Group: The hydroxymethyl group at the 5-position may enhance the compound's solubility and biological activity, making it a point of investigation for designing more effective pharmaceuticals.
  • Structural Diversity: The fusion of heterocyclic rings and a sugar-like unit, as seen in tetrahydrofuran, creates a compound that is not only structurally rich but also potentially versatile in its interactions with biomolecules.
  • Synthetic Challenges: The synthesis of such complex compounds is often fraught with challenges, potentially involving multiple reaction steps and conditions, thereby highlighting the ingenuity required in synthetic organic chemistry.
  • Research Relevance: Ongoing research into compounds like this one aims to uncover new treatments for diseases, including cancer and infectious diseases, due to their ability to interact with specific biochemical pathways.

In summary, 2-(7-aminoimidazo[4,5-b]pyridin-3-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is not just a chemical entity; it represents the complexities and innovations at the intersection of chemistry and biology. Understanding its properties and potential applications sheds light on exciting new frontiers in drug development.

Synonyms
SCHEMBL12556357
PD093854