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Tacrine hydrochloride benzylate

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Identification
Molecular formula
C19H22ClN3O2S
CAS number
168602-10-6
IUPAC name
2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylpropyl-trimethyl-ammonium
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.00
Boiling point (Celsius)
334.50
Boiling point (Kelvin)
607.65
General information
Molecular weight
418.92g/mol
Molar mass
418.9230g/mol
Density
1.3500g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylpropyl-trimethyl-ammonium

The solubility of the compound 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylpropyl-trimethyl-ammonium can be quite intricate, largely due to its unique chemical structure and presence of positively charged ammonium groups. Here are some key points to consider:

  • Polarity: The compound contains a quaternary ammonium structure, which generally enhances its solubility in polar solvents such as water.
  • Hydrophilicity: The presence of the sulfanylpropyl group may increase water solubility due to its ability to interact through hydrogen bonding.
  • Solvent Effects: In organic solvents like ethanol or methanol, solubility may vary. Adding alkyl substituents can enhance solubility in non-polar environments.
  • Temperature Dependency: As with many compounds, solubility can be temperature-dependent, often increasing with higher temperatures.
  • pH Influence: The solubility might also fluctuate with pH changes, as it can affect the ionization state of the ammonium group.

In summary, the solubility of this compound is influenced by its ionic character, structural components, and external conditions. As noted in many scientific assessments, compounds featuring quaternary ammonium structures are generally soluble in water due to their ionic nature, making them significant in various chemical and biomedical applications.

Interesting facts

Interesting Facts about 2-(7-chloro-4-oxo-3-phenyl-quinazolin-2-yl)sulfanylpropyl-trimethyl-ammonium

This remarkable compound belongs to a class of chemicals known for their versatility and potential applications in various fields, including medicinal chemistry. Here are some fascinating insights about this compound:

  • Structure and Function: The unique structure of this compound, featuring a quinazoline ring, grants it the potential to exhibit interesting biological activities. Quinazolines are known for their therapeutic properties, often acting as scaffolds in drug development.
  • Biological Relevance: Research surrounding quinazoline derivatives has indicated their potential in treating a range of diseases, including cancer and inflammatory disorders. This compound may leverage the biological activity associated with quinazoline to facilitate similar effects.
  • Ion Exchange Capability: The presence of the trimethyl-ammonium group could suggest interesting ion-exchange properties. Compounds like these are often studied for their ability to interact with cellular membranes or proteins, which could be beneficial for targeted drug delivery systems.
  • Chlorine Atom Influence: The incorporation of a chlorine atom into the molecular structure might enhance the compound's lipophilicity, affecting how it interacts with biological systems and possibly increasing its potency as an inhibitor in various pathways.
  • Potential Applications: Due to its complex structure, this compound could serve as a basis for investigating new pharmaceuticals, especially in areas like antimicrobial therapies or for selective enzyme inhibitors.

As researchers continue to explore compounds like this one, the potential for discovering new, effective treatments remains a driving force in the field of chemistry. The intricate relationship between structure and biological activity underscores the significance of such compounds in advancing medical science.