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7-Methoxytryptamine

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Identification
Molecular formula
C11H14N2O
CAS number
3178-96-9
IUPAC name
2-(7-methoxy-1H-indol-3-yl)ethanamine
State
State

At room temperature, 7-Methoxytryptamine is generally a solid. Its crystalline or powder form is stable under standard conditions.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
348.25
Boiling point (Kelvin)
621.40
General information
Molecular weight
190.24g/mol
Molar mass
190.2380g/mol
Density
1.2490g/cm3
Appearence

7-Methoxytryptamine is typically observed as a crystalline solid. It may appear as a white to pale yellow powder, which is typical for many tryptamine derivatives, especially those with methoxy substitutions.

Comment on solubility

Solubility of 2-(7-methoxy-1H-indol-3-yl)ethanamine

The solubility of 2-(7-methoxy-1H-indol-3-yl)ethanamine can be influenced by several factors, including its chemical structure and the solvent used. Generally, indole derivatives exhibit diverse solubility profiles due to their ability to engage in various intermolecular interactions.

Key points regarding its solubility include:

  • Polarity: The presence of the methoxy group may enhance polar interactions, potentially increasing solubility in polar solvents like water.
  • Hydrogen bonding: The amine group in the compound can participate in hydrogen bonding, which can facilitate solubility in protic solvents.
  • Solvent choice: The solubility will vary significantly depending on whether the solvent is organic (e.g., ethanol, DMSO) or aqueous.

Thus, while the compound may show reasonable solubility in polar solvents, its solubility in non-polar solvents could be considerably lower. It is essential to conduct specific solubility tests under controlled conditions to determine the exact solubility characteristics.

Interesting facts

Interesting Facts about 2-(7-methoxy-1H-indol-3-yl)ethanamine

2-(7-methoxy-1H-indol-3-yl)ethanamine, commonly referred to in scientific literature, is an intriguing compound that draws interest for its potential biological activities. Below are several key facts that illustrate the significance and utility of this compound:

  • Structure and Function: The compound features a unique indole structure, which is known for its role as a fundamental building block in a variety of natural products and pharmaceuticals. The presence of the methoxy group at position 7 enhances its chemical properties, impacting how it interacts with biological systems.
  • Biological Relevance: Compounds with indole scaffolds have shown a wide range of pharmacological effects including anti-inflammatory, anticancer, and antimicrobial activities. This can render 2-(7-methoxy-1H-indol-3-yl)ethanamine of significant interest for medicinal chemistry research.
  • Potential Therapeutic Applications: There are ongoing studies investigating the potential use of indole derivatives in the treatment of neurological disorders. The compound's structure may allow it to interact with neurotransmitter systems, presenting avenues for therapeutic innovations.
  • Synthetic Pathways: The synthesis of 2-(7-methoxy-1H-indol-3-yl)ethanamine may involve advanced organic chemistry techniques that highlight the creativity and ingenuity of chemists. This can include methods such as C–N bond formation, which is a critical reaction in constructing amines from aromatic precursors.
  • Nature's Inspiration: Indoles and their derivatives are often found in various natural sources, including plants and fungi. This emphasizes the importance of nature as a source of inspiration for the development of new drugs and compounds.

Overall, the study of 2-(7-methoxy-1H-indol-3-yl)ethanamine is emblematic of the rich interplay between chemical structure and biological function. The compound serves as a testament to the wonders of natural product chemistry and its role in drug discovery.

Synonyms
7-Methoxytryptamine
2-(7-METHOXY-1H-INDOL-3-YL)ETHAN-1-AMINE
855-689-8
2436-04-6
2-(7-Methoxy-1H-indol-3-yl)ethanamine
1H-Indole-3-ethanamine, 7-methoxy-
CHEMBL3330644
2-(7-Methoxy-1H-indol-3-yl)-ethylamine
TimTec1_004263
SZ9QG5P86E
Oprea1_286774
Oprea1_555272
7-Methoxytryptamine, free base
SCHEMBL1424902
7-methoxy-1h-indole-3-ethanamine
HMS1546B17
Ba-2809
BDBM50025220
MFCD01115208
STK675040
AKOS005208368
FM30486
FS-6605
MB01710
Indole, 3-(2-aminoethyl)-7-methoxy-
Ethanamine, 2-(7-methoxy-3-indolyl)-
2-(7-methoxy-1H-indol-3-yl)-ethyl-amine
2-(7-Methoxy-1H-indol-3-yl)ethanamine #
CS-0132150
EN300-194466
G84575
M-3567
F2113-0518
Z1192378718
Indole, 3-(2-aminoethyl)-7-methoxy-, hydrochloride (Salt/Mix)