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Quinine ethyl sulfate

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Identification
Molecular formula
C16H24N2O2Cl2
CAS number
130-95-0
IUPAC name
[2-[(8-ethoxyquinolin-1-ium-5-yl)amino]-2-oxo-ethyl]-isopropyl-ammonium;dichloride
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
266.50
Boiling point (Kelvin)
539.65
General information
Molecular weight
324.43g/mol
Molar mass
324.4320g/mol
Density
1.3400g/cm3
Appearence

This compound appears as a white to off-white powder or crystalline solid. It is often hygroscopic and can have a bitter taste. It is soluble in alcohol and slightly soluble in water.

Comment on solubility

Solubility of [2-[(8-ethoxyquinolin-1-ium-5-yl)amino]-2-oxo-ethyl]-isopropyl-ammonium;dichloride

The solubility of the compound [2-[(8-ethoxyquinolin-1-ium-5-yl)amino]-2-oxo-ethyl]-isopropyl-ammonium;dichloride is an intriguing aspect due to its unique structural features. This compound, being a quaternary ammonium derivative, indicates a potential for high solubility in polar solvents, particularly water.

Factors Influencing Solubility:

  • Ionic Nature: The presence of dichloride suggests that ions are involved, which typically enhances solubility in aqueous solutions.
  • Hydrophilicity: The ethoxy and amino groups contribute to the hydrophilic character of the molecule, favoring interaction with water molecules.
  • Molecular Interactions: Hydrogen bonding with water can facilitate dissolution, especially due to the active sites on the aromatic and amino groups.

As a summary, the compound is likely to exhibit good solubility in polar solvents, primarily due to its ionic nature and the presence of functional groups capable of engaging in hydrogen bonding. Therefore, one might expect that the solubility of this compound will be notably enhanced in a physiologically relevant environment. However, experiments are necessary to quantify this solubility accurately and to assess its behavior in non-polar solvents, where solubility might significantly decrease.

Interesting facts

Interesting Facts about 2-[(8-ethoxyquinolin-1-ium-5-yl)amino]-2-oxo-ethyl]-isopropyl-ammonium;dichloride

This intriguing compound represents a unique class of organic compounds that integrates both amino and quinoline structures. Here are some notable aspects:

  • Quinoline Derivative: Quinoline is a bicyclic compound known for its diverse biological activities. This compound incorporates a quinoline moiety, enhancing its potential pharmacological properties.
  • Role of Ethoxy Group: The presence of the ethoxy group increases solubility and helps in enhancing biological interactions, making it a valuable feature in medicinal chemistry.
  • Potential Applications: Compounds containing quinoline derivatives have shown promise in applications ranging from antimalarial agents to treatment for certain cancers. This compound may similarly contribute to innovative therapeutic strategies.
  • Ammonium Ion: The isopropyl-ammonium ion in the structure adds a charged group, which can be crucial for interactions with biological membranes, potentially aiding in cellular uptake.
  • Chloride Formulation: The dichloride part of the compound not only influences solubility but may also play a role in maintaining stability and efficacy in biological systems.
  • Research Potential: Given its complex structure, this compound presents exciting opportunities for further research into its chemical reactivity and possible synthesis of new derivatives with enhanced properties.

With its combination of structural features, this compound could serve as a platform for the development of new drugs, showcasing the importance of chemical diversity in the realm of medicinal chemistry.

Synonyms
T 1138
N-(8-Ethoxy-5-quinolyl)-2-(isopropylamino)acetamide dihydrochloride
ACETAMIDE, N-(8-ETHOXY-5-QUINOLYL)-2-(ISOPROPYLAMINO)-, DIHYDROCHLORIDE
19655-40-4
RefChem:315470