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2-(8-Quinolylsulfanyl)ethanol

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Identification
Molecular formula
C11H11NOS
CAS number
138-61-8
IUPAC name
2-(8-quinolylsulfanyl)ethanol
State
State

At room temperature, 2-(8-quinolylsulfanyl)ethanol is typically found in a solid state.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
207.28g/mol
Molar mass
207.2820g/mol
Density
1.2350g/cm3
Appearence

2-(8-Quinolylsulfanyl)ethanol typically appears as a light yellow crystalline solid. Its appearance can vary slightly based on purity and form.

Comment on solubility

Solubility of 2-(8-quinolylsulfanyl)ethanol

When considering the solubility of 2-(8-quinolylsulfanyl)ethanol, it is essential to recognize several key factors that contribute to its behavior in different solvents. This compound is characterized by a unique structure that influences its interaction with various solvents.

Factors Influencing Solubility

  • Polarity: The presence of both the 8-quinolyl and sulfanyl functional groups contributes to the overall polarity of the molecule.
  • Hydrogen Bonding: The hydroxyl group (-OH) present in alcohols typically enhances solubility in polar solvents due to its ability to form hydrogen bonds.
  • Aromaticity: The aromatic nature of the quinoline ring can also affect solubility, as aromatic compounds often show variable solubility in water compared to aliphatic compounds.

Thus, 2-(8-quinolylsulfanyl)ethanol is expected to exhibit:

  1. Increased solubility in: polar solvents such as water and lower alcohols.
  2. Decreased solubility in: non-polar solvents such as hexane or cyclohexane.

In summary, the solubility of this compound is a result of its molecular structure, characterized by both polar and non-polar components, leading to a solubility profile that varies significantly with solvent choice. Understanding these solubility patterns can guide effective use in various chemical processes.

Interesting facts

Interesting Facts about 2-(8-quinolylsulfanyl)ethanol

2-(8-quinolylsulfanyl)ethanol is a fascinating compound that possesses unique chemical characteristics, influencing both its functionality and applications in various fields. Here are some intriguing aspects:

  • Quinoline Derivative: This compound is a derivative of quinoline, which is a bicyclic structure characterized by its nitrogen-containing aromatic ring. Quinoline derivatives are noteworthy in medicinal chemistry as they often exhibit biological activity.
  • Sulfur Atom: The presence of a sulfonyl group in the structure plays a pivotal role in enhancing the compound's reactivity. Sulfur is known for its ability to form diverse bonds, broadening the potential chemical applications of this compound.
  • Biological Activity: Compounds related to 2-(8-quinolylsulfanyl)ethanol have been investigated for their anti-microbial and anti-cancer properties. Research suggests that substitutions at the quinoline ring can lead to varied pharmacological activities.
  • Applications in Organic Synthesis: This compound can serve as a valuable building block in organic synthesis. Its functional groups allow for further chemical modifications that can lead to the creation of more complex molecules required in various research initiatives.
  • Potential in Material Science: The unique structure of 2-(8-quinolylsulfanyl)ethanol may also pave the way for its use in material science, particularly in the development of light-emitting devices and photonic applications.

In summary, 2-(8-quinolylsulfanyl)ethanol exemplifies the intersection of organic chemistry with real-world applications, showcasing the importance of functional groups and molecular structure in determining the compound's properties and potential uses. Its profile as a biologically active molecule continues to intrigue chemists and researchers alike, leading to sustained interest in its development and applications.

Synonyms
ETHANOL, 2-(8-QUINOLYLTHIO)-
7545-91-7
8-(2-Hydroxyethylthio)quinoline
BRN 0138214
Quinoline, 8-(2-hydroxyethylthio)-
DTXSID00226384
5-21-03-00305 (Beilstein Handbook Reference)
DTXCID00148875
2-quinolin-8-ylsulfanylethanol
Oprea1_478945
2-(8-quinolinylsulfanyl)ethanol
2-(quinolin-8-ylsulfanyl)ethanol
8-(2-hydroxyethylsulfanyl)quinoline
STL591726
AKOS024269554
AG-205/11944019