Fluocinolone acetonide

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Identification

Molecular formula
C24H30FNO6
CAS Number
67-73-2
IUPAC Name
[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] pyridine-4-carboxylate
Molecular Weight
452.50g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.3960g/cm3
Synonyms
DEXAMETHASONE ISONICOTINATE
Interesting facts

Interesting Facts about 2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] pyridine-4-carboxylate

This complex compound features several intriguing characteristics that make it a subject of interest in the field of organic chemistry and medicinal research.

  • Stereochemistry: The compound displays a rich stereochemical landscape, with multiple chiral centers. This complexity can lead to varied biological activities, making stereoisomerism a crucial aspect in the study of its pharmacological properties.
  • Original Use: This compound is synthesized for its potential therapeutic applications, particularly in the fields of oncology and hormone modulation. Its structure suggests it might interact with steroid receptors, which could be beneficial in hormone-related disorders.
  • Fluorine Substitution: The inclusion of a fluorine atom enhances metabolic stability and alters lipophilicity. This makes the compound more appealing for development as a drug, as fluorinated compounds often exhibit improved bioavailability.
  • Framework: The presence of multiple cyclic structures, including an octahydrocyclopenta[a]phenanthrene moiety, indicates a complex molecular backbone that could influence its interaction with biological targets, leading to unique mechanisms of action.

As scientists continue to explore the therapeutic potential of compounds with intricate frameworks like this one, we are reminded of the importance of structure-activity relationships in drug design. It is a dance of atoms and forces that promises exciting discoveries in the quest for innovative treatments.

The study of such compounds reveals the *artistry of chemistry*, where nature's building blocks can lead to transformative medicinal advances.

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