Interesting facts
Interesting Facts about 2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] propanoate
This complex organic compound is notable for its unique structural characteristics and potential applications in medicinal chemistry. Here are some captivating aspects:
- Stereochemistry: The compound exhibits specific stereochemical centers, indicated by the (S) and (R) designations. These configurations are critical because they can influence the compound's interactions with biological systems, showcasing the importance of stereochemistry in pharmacology.
- Fluorinated compound: The presence of a fluorine atom enhances the compound’s lipophilicity, which can improve its membrane permeability, making it an attractive candidate for drug development.
- Bioactivity: Compounds like this one have been studied for their potential biological activities, including anti-inflammatory and anti-cancer properties, indicating that they could play a role in future therapeutic strategies.
- Complexity: The intricate structure, including multiple rings and functional groups, challenges chemists in terms of synthesis and characterization, representing an exciting area of research in organic synthesis.
- Analytical methods: To analyze and characterize this compound, sophisticated techniques such as NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry) are often employed, providing insight into its structure and properties.
As chemists continue to explore the potential of such complex compounds, they open the door to developing new therapeutics and understanding the mechanisms underlying their biological effects. The synthesis and exploration of molecules like this one also contribute significantly to the rich tapestry of medicinal chemistry, where every new discovery has the potential to change lives.
Synonyms
BETAMETHASONE DIPROPIONATE
Diprolene
Diprosone
Alphatrex
Maxivate
Diprolene AF
Diproderm
Psorion
Rinderon DP
Diprosis
Sch 11460
Sernivo
Sch-11460
Rinderon-DP
EINECS 227-005-2
S-3440
BRN 3638108
Betamethasone (as dipropionate)
DTXSID2022672
CHEBI:31276
UNII-826Y60901U
S 3440
NSC-758415
DTXCID302672
826Y60901U
NSC 758415
Betamethasone dipropionate [USAN:USP:JAN]
BETAMETHASONE DIPROPIONATE, AUGMENTED
ENSTILAR COMPONENT BETAMETHASONE DIPROPIONATE
TACLONEX COMPONENT BETAMETHASONE DIPROPIONATE
WYNZORA COMPONENT BETAMETHASONE DIPROPIONATE
LOTRISONE COMPONENT BETAMETHASONE DIPROPIONATE
LEO-90100 COMPONENT BETAMETHASONE DIPROPIONATE
BETAMETHASONE DIPROPIONATE (MART.)
BETAMETHASONE DIPROPIONATE [MART.]
BETAMETHASONE DIPROPIONATE (USP-RS)
BETAMETHASONE DIPROPIONATE [USP-RS]
Betamethasone dipropionate (USAN:USP:JAN)
BETAMETHASONE DIPROPIONATE (EP MONOGRAPH)
BETAMETHASONE DIPROPIONATE [EP MONOGRAPH]
BETAMETHASONE DIPROPIONATE (USP MONOGRAPH)
BETAMETHASONE DIPROPIONATE [USP MONOGRAPH]
Betamethasone DipropionateAugmented
Betamethasone Dipropionate USP, 0.05%
BETAMETHASONE DIPROPIONATE COMPONENT OF ENSTILAR
BETAMETHASONE DIPROPIONATE COMPONENT OF TACLONEX
BETAMETHASONE DIPROPIONATE COMPONENT OF WYNZORA
BETAMETHASONE DIPROPIONATE COMPONENT OF LOTRISONE
BETAMETHASONE DIPROPIONATE COMPONENT OF LEO-90100
227-005-2
5593-20-4
Betamethasone 17,21-dipropionate
Diprospan
Betamethasone-17,21-dipropionate
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
(11-beta,16-beta)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate
beta-Methasone 17,21-dipropionate
.beta.-Methasone 17,21-dipropionate
Betamethasone Dipropionate (Diprolene)
Diprolene (TN)
NCGC00159360-02
NCGC00159443-02
Sernivo (TN)
Rinderon-DP (TN)
betamethasone-dipropionate
BETAMETHASONE DIPROP
SCHEMBL7519
9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)
Betamethasone-17,21-dipropionate 100 microg/mL in Acetonitrile
CHEMBL1200384
component of Betasone (Salt/Mix)
GLXC-23134
component of Alphatrex (Salt/Mix)
Tox21_113343
BDBM50421892
Betamethasone dipropionate (Standard)
HY-13571R
s1688
AKOS015969733
Betamethasone dipropionate (JP18/USP)
CCG-269732
CS-7549
FB36997
KS-5303
BETAMETHASONE DIPROPIONATE [JAN]
BETAMETHASONE DIPROPIONATE [USAN]
NCGC00159443-01
NCGC00159443-05
2-((2S,10S,11S,13S,15S,17S,1R,14R)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxo -14-propanoyloxytetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-3,6-dien-14-yl)-2-o xoethyl propanoate
BETAMETHASONE DIPROPIONATE [VANDF]
HY-13571
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 17,21-dipropionate
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)
BETAMETHASONE DIPROPIONATE [WHO-DD]
CAS-5593-20-4
B3166
NS00005151
BETAMETHASONE 17,21-DIPROPIONATE [MI]
BETAMETHASONE DIPROPIONATE [GREEN BOOK]
BETAMETHASONE DIPROPIONATE [ORANGE BOOK]
D01637
AB01274713-01
AB01274713_02
BETAMETHASONE 17.ALPHA.,21-DIPROPIONATE
Q4897349
BRD-K58148589-001-03-6
(11.beta.,16.beta.)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
(11beta,16beta)-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
9-Fluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
9-Fluoro-11.beta.-hydroxy-16.beta.-methyl-3,20-dioxo-17-(propionyloxy)pregna-1,4-dien-21-yl propionate #
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17,21-Dipropionate
9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene- 17,21-diyl dipropionate
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-.beta.,17,21-trihydroxy-16-.beta.-methyl-,17,21-dipropionate
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11-HYDROXY-16-METHYL-17,21-BIS(1-OXOPROPOXY)-, (11.BETA.,16.BETA.)
Solubility of 2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl propanoate
The solubility of 2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl propanoate can exhibit specific characteristics due to its complex molecular structure.
In summary, while this compound may hold promise for solubility in specific polar solvents, its overall behavior will likely lean towards greater solubility in organic media amidst a complex interplay of molecular interactions that warrant careful study.