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Halcinonide

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Identification
Molecular formula
C24H32ClFO5
CAS number
3093-35-4
IUPAC name
[2-[(9R,11S,14S,16R,17S)-16-acetoxy-9-chloro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
State
State

Halcinonide is a solid at room temperature. It is used in pharmaceutical preparations and often presented as a topical cream or ointment for ease of application to the skin.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
455.97g/mol
Molar mass
455.9430g/mol
Density
1.3800g/cm3
Appearence

Halcinonide is a white to off-white crystalline powder. It is typically supplied in the form of a topical cream or ointment for pharmaceutical applications. The powder has a characteristic odor.

Comment on solubility

Solubility Overview

The compound 2-[(9R,11S,14S,16R,17S)-16-acetoxy-9-chloro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl acetate can present a complex solubility profile due to its intricate molecular structure. Understanding the solubility characteristics of such compounds is vital for their application and study. Here are some factors affecting its solubility:

  • Polarity: The presence of polar functional groups such as hydroxyl (–OH) and acetate (–OCOCH3) may increase the compound's solubility in polar solvents like water and alcohols.
  • Stereochemistry: The compound contains multiple chiral centers, impacting how it interacts with solvents and might alter solubility in different environments.
  • Hydrophobic regions: Non-polar sections of the molecule could lead to lower solubility in polar solvents but better solubility in non-polar solvents or organic solvents.
  • Temperature: Solubility can vary with temperature; generally, solubility increases with temperature for many compounds.

In summary, the solubility of this intricate compound may not be straightforward and can vastly differ based on the solvent used, the temperature, and its overall molecular structure. It is essential to perform empirical solubility tests to ascertain its behavior in various solvents for practical applications. As the saying goes, "like dissolves like," and this principle will guide your explorations of its solubility characteristics.

Interesting facts

Interesting Facts about 2-[(9R,11S,14S,16R,17S)-16-acetoxy-9-chloro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl acetate

This complex chemical compound is a fascinating example of the intricate nature of organic chemistry. It belongs to a class of compounds known for their diverse biological activities and therapeutic potential. Here are some key insights:

  • Structural Complexity: The compound features a multi-ring structure that is characteristic of steroid-like molecules. This reflects its potential interactions with biological systems.
  • Biological Significance: Due to its unique functional groups, the compound could exhibit *hormonal* or *antineoplastic* properties. Compounds like these are often studied for their medicinal applications, particularly in treating various forms of cancer.
  • Chirality: The presence of multiple stereocenters in its structure indicates chirality, which is crucial in pharmacology as different enantiomers can have vastly different biological activities.
  • Research Potential: Scientists are excited about compounds of this nature owing to their potential in drug design and synthesis, particularly in crafting targeted therapies that minimize side effects.

In the realm of medicinal chemistry, this compound serves as a prime example of how intricate designs can lead to novel therapeutic agents. As researchers continue to study compounds like this, we may unlock new aspects of cellular biology and improve drug efficacy.

As one researcher aptly states, “The beauty of organic chemistry lies in its complexity and the surprising ways these compounds can fit into the labyrinth of life.” This encapsulates the ongoing journey in understanding compounds like 2-[(9R,11S,14S,16R,17S)-16-acetoxy-9-chloro-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl acetate.