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Acetaminophen

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Identification
Molecular formula
C8H9NO2
CAS number
103-90-2
IUPAC name
2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid
State
State
At room temperature, acetaminophen is a solid. This compound is stable under normal conditions and is usually found as a crystalline powder or as a compacted tablet for pharmaceutical purposes.
Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.5450g/cm3
Appearence

Acetaminophen typically appears as white, crystalline powder. It is odorless and has a slightly bitter taste. It is commonly available in tablet form for medicinal use, appearing as solid, compressed tablets often coated for easier ingestion.

Comment on solubility

Solubility of 2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid

The solubility of 2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid is influenced by several factors, which can be summarized as follows:

  • Polarity: This compound has polar functional groups, including an amide and a carboxylic acid, which can interact favorably with polar solvents such as water.
  • Hydrogen Bonding: Its ability to form hydrogen bonds enhances its solubility in aqueous environments, promoting dissolution in polar solvents.
  • Ionic Interaction: The presence of the carboxylic acid group may also facilitate ionic interactions, especially at neutral to basic pH levels.
  • Temperature Dependency: Like many organic acids, solubility may also increase with temperature, making it more soluble in heated solvents.

In summary, while there is potential for good solubility in polar solvents due to its structural features, the specific solubility behavior of 2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid can still vary based on environmental conditions such as temperature and pH.

Interesting facts

Interesting Facts about 2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid

2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid, often abbreviated as a complex compound, is notable for its diverse applications in both organic chemistry and pharmaceuticals. Here are some captivating aspects that might intrigue both scientists and chemistry students:

  • Pharmacological Significance: This compound is investigated for its potential use in drug development. The presence of the iodine atom can influence its biological activity, making it a point of interest for medicinal chemistry.
  • Vital Functional Groups: The compound boasts several functional groups, including an acetamido group and a hydroxyl group. These contribute to its reactivity and solubility, important features when designing derivatives for practical applications.
  • Research Applications: Its structural complexity makes it a valuable candidate for studies on structure-activity relationships (SAR) in drug development. Researchers aim to understand how modifications affect biological activity.
  • Analytical Techniques: This compound serves as a great subject for various analytical techniques such as NMR, mass spectrometry, and crystallography, offering students the opportunity to gain hands-on experience in the lab.
  • Environmental Impact: With growing concerns about the environmental impact of chemical waste, the synthesis and degradation pathways of this compound are areas of active research, aiming to minimize ecological footprints.

In summary, 2-acetamido-3-(4-hydroxy-3-iodo-phenyl)propanoic acid not only stands out for its intricate chemical structure but also opens doors to valuable conversations about its biochemical potential and environmental considerations. As chemists explore its applications, they contribute to a broader understanding of both chemistry and pharmacology.

Synonyms
N-ACETYL-3-IODO-L-TYROSINE
Levothyroxine Sodium Impurity 15
1023-47-8
SCHEMBL468853
BCP34166
AB03770
17597-67-0
propanoic acid, 2-acetylamino-3-(4-hydroxy-3-iodophenyl)-
N-Acetyl-3-iodo-L-tyrosine;Tyrosine, N-acetyl-3-iodo-, DL-