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Meropenem

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Identification
Molecular formula
C17H25N3O5S
CAS number
119478-56-7
IUPAC name
2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide
State
State

At room temperature, meropenem is in a solid state as a crystalline powder.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.15
Boiling point (Celsius)
430.00
Boiling point (Kelvin)
703.15
General information
Molecular weight
383.46g/mol
Molar mass
383.4580g/mol
Density
1.6800g/cm3
Appearence

Meropenem typically appears as a white to pale yellow crystalline powder. When used in pharmaceutical formulations, it may be reconstituted into a clear to pale yellow solution depending on the solvent used.

Comment on solubility

Solubility of 2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide

The solubility of 2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide (C17H25N3O5S) is influenced by several factors, primarily its molecular structure and functional groups. Understanding the solubility properties of this compound can be crucial in various applications.

  • Polarity: The presence of multiple functional groups, such as amides and carbamates, generally enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The amido (-CONH-) and carbonyl groups present allow the molecule to engage in hydrogen bonding, which further promotes its solubility in polar environments.
  • Hydrophobic Character: The long aliphatic chains contribute to hydrophobic interactions, which may reduce solubility in strictly polar solvents.

Overall, the solubility of this compound is expected to be moderate in aqueous solutions, likely exhibiting increased solubility in organic solvents due to its hydrophobic components. As with many chemical compounds, the actual solubility will depend on precise conditions such as temperature, pH, and the presence of other solutes.

In summary:

  1. Moderate solubility in polar solvents.
  2. Enhanced solubility due to hydrogen bonding capabilities.
  3. Possible reduced solubility in extremely non-polar solvents.

By examining these aspects, researchers can better predict the behavior and interactions of 2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide in various environments.

Interesting facts

Interesting Facts about 2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide

This intriguing compound, known as 2-acetamido-N-[1-(1-formylpentylcarbamoyl)-3-methyl-butyl]-4-methyl-pentanamide, plays a fascinating role in the world of medicinal chemistry. Here are some compelling insights:

  • Drug Design and Development: Its complex structure suggests potential applications in drug design, specifically for targeting various physiological pathways within the body.
  • Functional Groups: The presence of multiple functional groups, such as acetamido and carbamoyl, indicates that this compound may exhibit diverse biological activities and could interact with different cellular targets.
  • Structure-Activity Relationship: Researchers are likely to be interested in exploring how modifications to its structure affect its biological efficacy. This could lead to the development of more effective drug analogs.
  • Potential Therapeutic Uses: Given its structural complexity, it may have potential applications in treating conditions such as inflammation, pain management, or even targeted cancer therapy.
  • Historical Context: Compounds with similar backbone structures have been historically significant in the development of pharmaceuticals, revealing a pattern in the optimization of drug-like properties.

Furthermore, chemists often emphasize the importance of studying compounds like this one as they contribute to the broader understanding of chemical interactions and drug formulation. As quoted by a renowned chemist, “The beauty of medicinal chemistry lies in how small changes to a molecule can yield significant differences in therapeutic outcomes.”

Research into compounds of this nature not only expands our knowledge of chemistry but also paves the way for innovative solutions to pressing health issues around the globe.

Synonyms
N-Acetyl-leucyl-leucyl-norleucinal
MG101
SCHEMBL258985
Ac-Leu-Leu-Nle-H (Aldehyde)
IAL-3671-PI
BCP28014
2-acetamido-4-methyl-N-[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]pentanamide
DB-040894
2-acetamido-4-methyl-N-{3-methyl-1-[(1-oxohexan-2-yl)carbamoyl]butyl}pentanamide