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Lacosamide

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Identification
Molecular formula
C13H18N2O3
CAS number
175481-36-4
IUPAC name
2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide
State
State

At room temperature, lacosamide is a solid. It is typically dry and crystalline in a stable, solid form.

Melting point (Celsius)
143.50
Melting point (Kelvin)
416.65
Boiling point (Celsius)
380.50
Boiling point (Kelvin)
653.50
General information
Molecular weight
250.32g/mol
Molar mass
250.3170g/mol
Density
1.3050g/cm3
Appearence

Lacosamide is a white to off-white crystalline powder. It is known for its stability in dry conditions.

Comment on solubility

Solubility of 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide

The compound 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide, with the chemical formula C13H18N2O3, exhibits unique solubility characteristics that are influenced by its molecular structure.

Key Points on Solubility:

  • Polar Functional Groups: The presence of amides and a carbonyl group within the molecule can enhance its solubility in polar solvents such as water.
  • Non-Polar Sections: The benzyl and alkyl groups contribute to a degree of non-polarity, suggesting reduced solubility in highly polar solvents.
  • Solvent Interactions: The overall solubility is typically better in solvents like DMSO or methanol compared to non-polar solvents like hexane.
  • Temperature Dependence: Solubility may increase with temperature, allowing for better dissolution of the compound in various solvents.

It is often noted that solubility can be greatly affected by temperature and pH; thus, conducting solubility tests under controlled conditions can yield more accurate data. Ultimately, the balance of polar and non-polar characteristics in 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide plays a crucial role in determining its suitability for different applications, making understanding its solubility essential for practical use.

Interesting facts

Interesting Facts about 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide

The compound 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide is an intriguing member of the amide family, and it offers unique characteristics that reveal its potential applications and importance in various fields of science.

Chemical Structure and Function

This compound can be analyzed through its structural features, which include:

  • Amide Group: The presence of an amide functional group contributes to its reactivity and solubility properties.
  • Aromatic Benzyl Moiety: The benzyl portion of the compound enhances its interaction with biological targets due to π-π stacking interactions.
  • Keto Group: The inclusion of a keto group can influence the compound's reactivity and stability, particularly in biochemical pathways.

Potential Applications

Given its unique structure, this compound shows promise in several areas:

  • Pharmaceutical Research: It may serve as a scaffold for the development of novel drugs aimed at treating various diseases, particularly those requiring specificity in targeting.
  • Biocatalysis: The compound’s structure suggests that it might be used in enzyme-mediated processes due to its functional groups that can serve as substrates or inhibitors.

Biological Relevance

Research into related compounds indicates that amides often play significant roles in:

  • Protein Interactions: The amide bond is prevalent in protein backbones, which means compounds like this can be critical in studying molecular interactions.
  • Enzyme Substrates: The specific structure of this compound could render it a good candidate for exploring enzyme specificity and catalytic mechanisms in biological systems.

In summary, 2-acetamido-N-(1-benzyl-2-oxo-ethyl)-4-methyl-pentanamide captivates scientific attention due to its potential implications in drug design, biological interactions, and enzyme studies. The ongoing exploration of compounds like this contributes immensely to our understanding of chemistry and its applications in medicine and biotechnology.

Synonyms
PD037067