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Cyclosporin

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Identification
Molecular formula
C62H111N11O12
CAS number
59865-13-3
IUPAC name
2-acetamido-N-[3-[[(2-acetamido-3-methyl-butanoyl)amino]-(cyclohexylmethyl)amino]-1-benzyl-2-hydroxy-propyl]-3-methyl-butanamide
State
State

At room temperature, Cyclosporin is in a solid state. It is characterized by its stability as a crystalline powder.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1202.61g/mol
Molar mass
1 202.6100g/mol
Density
1.0370g/cm3
Appearence

Cyclosporin is a crystalline solid with no distinct color, generally appearing white. Its appearance can vary depending on the manufacturer, but it is typically seen as a powder or fine crystals.

Comment on solubility

Solubility of 2-acetamido-N-[3-[[[2-acetamido-3-methyl-butanoyl]amino]-(cyclohexylmethyl)amino]-1-benzyl-2-hydroxy-propyl]-3-methyl-butanamide

The solubility of complex organic compounds, such as 2-acetamido-N-[3-[[[2-acetamido-3-methyl-butanoyl]amino]-(cyclohexylmethyl)amino]-1-benzyl-2-hydroxy-propyl]-3-methyl-butanamide (C62H111N11O12), can vary dramatically based on various factors. Due to its large molecular structure, one might anticipate several influential aspects affecting its solubility.

  • Polarity: The presence of multiple amide groups may enhance interactions with polar solvents, potentially increasing solubility in water.
  • Hydrophobic Regions: Sections of cyclohexyl and benzyl groups introduce hydrophobic characteristics, making the compound less soluble in highly polar solvents.
  • Temperature: Solubility can be temperature-dependent; elevated temperatures may improve solubility through increased kinetic energy.

Moreover, it is important to consider the pH of the solvent, which could affect the protonation states of functional groups, thus altering solubility properties. Additionally, measuring solubility in varied solvents could yield further insights into the compound's behavior in diverse environments. In summary, while specific solubility data for this compound is not readily available, its solubility is likely influenced by a combination of its comprehensive molecular structure, the nature of the solvent, and external conditions such as temperature and pH.

Interesting facts

Interesting Facts about 2-acetamido-N-[3-[[[2-acetamido-3-methyl-butanoyl]amino]-(cyclohexylmethyl)amino]-1-benzyl-2-hydroxy-propyl]-3-methyl-butanamide

This compound is a fascinating example of a complex organic molecule, showcasing the intricate nature of medicinal chemistry. Here are some intriguing aspects of this compound:

  • Complex Structure: The molecule displays multiple functional groups, including amides and hydroxyl groups, contributing to its chemical behavior. Such complexities often challenge synthetic chemists but can also lead to innovative therapeutic properties.
  • Potential Therapeutic Application: Compounds with amide linkages are common in pharmaceuticals. They often exhibit significant biological activity due to their ability to form hydrogen bonds, which can enhance interactions with biological targets.
  • Cyclic Structure Influence: The presence of a cyclohexyl group implies potential steric hindrance, affecting the compound’s interaction with enzymes and receptors. This can be crucial in designing inhibitors for specific biological pathways.
  • Hydrophobic Character: The large hydrophobic regions within this molecule may influence its solubility and permeability, vital for drug development. Logically, compounds that balance hydrophobic and hydrophilic characteristics are often more successful as therapeutic agents.
  • Importance of Acetamido Groups: Acetamido groups often enhance the stability and bioavailability of drug molecules. Their role in this compound may contribute to its pharmacokinetic properties.

In conclusion, 2-acetamido-N-[3-[[[2-acetamido-3-methyl-butanoyl]amino]-(cyclohexylmethyl)amino]-1-benzyl-2-hydroxy-propyl]-3-methyl-butanamide is not just a string of atoms but a potential powerhouse in the world of medicinal chemistry. Studying such compounds enhances our understanding of molecular behavior, which is pivotal for future drug design.