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Glycine

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Identification
Molecular formula
C4H7NO3
CAS number
543-24-8
IUPAC name
2-acetamidoacetic acid
State
State

At room temperature, 2-acetamidoacetic acid is typically in a solid state.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
117.12g/mol
Molar mass
117.1190g/mol
Density
1.5950g/cm3
Appearence

2-acetamidoacetic acid, also known as Glycine, is a white, crystalline solid under normal conditions. It is known for its sweet taste and is the simplest stable amino acid. Glycine is often used in aqueous solutions due to its solubility properties.

Comment on solubility

Solubility of 2-acetamidoacetic acid

2-acetamidoacetic acid, also known as acetylglycine, presents an interesting profile when it comes to solubility.

Solubility Characteristics

This compound is found to be:

  • Soluble in water: 2-acetamidoacetic acid exhibits good solubility in polar solvents, primarily water, due to its ability to form hydrogen bonds.
  • Moderately soluble in alcohols: Alcohols like ethanol also facilitate the dissolution of this compound, although the solubility tends to be less than in water.
  • Insoluble in non-polar solvents: Non-polar solvents, such as hexane or chloroform, do not dissolve 2-acetamidoacetic acid effectively, highlighting the importance of polarity in solvation.

In general, the solubility of 2-acetamidoacetic acid is influenced by factors such as:

  • The presence of functional groups (like the amido and carboxylic acid functional groups) that can interact with solvent molecules.
  • Temperature, where increased temperature often leads to enhanced solubility.

Overall, the solubility of 2-acetamidoacetic acid is pivotal for its applications in various chemical processes, especially in biochemistry and pharmaceuticals.

Interesting facts

Interesting Facts about 2-Acetamidoacetic Acid

2-Acetamidoacetic acid, also known as glycylacetamide, is a compound that sits at the intersection of amino acids and acetamides. Here are some engaging insights into this intriguing molecule:

  • Biochemical Relevance: This compound serves as a critical intermediate in the synthesis of various amino acids and is valuable in biochemical research, particularly in the study of protein interactions.
  • Pharmaceutical Applications: Due to its structural similarity to amino acids, 2-acetamidoacetic acid can play a role in drug design, particularly for targeting metabolic pathways and enzyme activities.
  • Modifications and Derivatives: The potential for modification of 2-acetamidoacetic acid has led to various derivatives, which are being explored for their biological activities. These derivatives may exhibit changes in properties such as solubility and reactivity, opening doors for innovative applications.
  • Environmental Impact: Research suggests that the use of compounds like 2-acetamidoacetic acid in agricultural formulations may contribute to more sustainable practices, as they can enhance nutrient uptake in plants.
  • Structure and Function: The unique structure of 2-acetamidoacetic acid allows it to participate in hydrogen bonding, which is crucial for its interaction with biological macromolecules.

In summary, 2-acetamidoacetic acid is not just another compound; it plays a significant role in both synthetic and natural processes that are vital to our understanding of biology and medicine. As we keep discovering new applications, its importance will only continue to grow!

Synonyms
N-ACETYLGLYCINE
Aceturic acid
Acetylglycine
Glycine, N-acetyl-
ACETYLAMINO-ACETIC ACID
N-acetyl-glycine
(acetylamino)acetic acid
Acetyl Glycine
2-(Acetylamino)acetic acid
aceturate
acetamidoacetate
Ac Gly
UNII-U2UT4677KR
ethanoylaminoethanoate
acetylaminoacetate
CHEBI:40410
CH3CONHCH2COOH
NSC-7605
EINECS 208-839-6
N-acetylglycine sodium salt
ACETURIC ACID [MI]
15N-acetylglycine a-radical
AI3-17738
DTXSID2043793
NAcetylglycine
Glycine, Nacetyl
Acetylamino-acetate
DTXCID0023793
inchi=1/c4h7no3/c1-3(6)5-2-4(7)8/h2h2,1h3,(h,5,6)(h,7,8
okjirpaqvshgfk-uhfffaoysa-n
543-24-8
2-Acetamidoacetic acid
Ac-Gly-OH
Acetamidoacetic acid
Acetylaminoacetic acid
Acetylglycocoll
Ethanoylaminoethanoic acid
2-acetamidoacetate
MFCD00004275
NSC 7605
Acetyl-glycine
U2UT4677KR
acetyl-glycin
N-acetyl glycine
bmse000610
N-Acetylglycine (Standard)
SCHEMBL5876
CHEMBL289004
BDBM82197
HY-Y0069R
NSC7605
ALBB-019763
HY-Y0069
AC8343
BBL020087
s3098
STK256622
AKOS000118774
AB00351
CS-W020121
DB02713
FA10861
N-Acetylglycine, ReagentPlus(R), 99%
NCGC00320093-01
AC-24104
AS-12785
SY013515
DB-030111
A0093
Acetamidoacetic acid;Aceturic acid;Ac-Gly-OH
EU-0096429
NS00015106
EN300-18561
AB00374931-02
AB00374931-04
N-Acetylglycine, Vetec(TM) reagent grade, 98%
10.14272/OKJIRPAQVSHGFK-UHFFFAOYSA-N.1
AB-131/40177771
N-Acetylglycine Acetylglycine Acetamidoacetic acid
doi:10.14272/OKJIRPAQVSHGFK-UHFFFAOYSA-N.1
Q15634040
Z85886676
19FC14B9-9BF4-46B1-9A63-D3B6CFB535ED
F0921-6976
Acetamidoacetic acid; Aceturic acid; Aceturic acid; Acetamidoacetic acid