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N-Acetylglutamic acid

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Identification
Molecular formula
C7H11NO5
CAS number
1188-37-0
IUPAC name
2-acetamidopentanedioic acid
State
State

At room temperature, N-Acetylglutamic acid is a solid. It is typically handled as a powder in laboratory settings. It is stable under recommended storage conditions.

Melting point (Celsius)
194.50
Melting point (Kelvin)
467.60
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
189.18g/mol
Molar mass
189.1770g/mol
Density
1.5200g/cm3
Appearence

N-Acetylglutamic acid typically appears as a white crystalline powder. It may have a slight odor and is often used in biochemical applications due to its role as an intermediate in amino acid metabolism.

Comment on solubility

Solubility of 2-acetamidopentanedioic acid

2-acetamidopentanedioic acid, with the chemical formula C7H11NO5, exhibits interesting solubility characteristics due to its organic acid structure. Its solubility can be influenced by several factors:

  • Polarity: This compound contains multiple polar functional groups (like carboxylic acids and an amide), which enhances its ability to dissolve in polar solvents, such as water.
  • Hydrogen Bonding: The presence of amine and carboxyl groups allows for significant hydrogen bonding with water molecules, further promoting solubility in aqueous solutions.
  • Temperature: Generally, increasing temperature can improve the solubility of organic acids; hence, 2-acetamidopentanedioic acid may dissolve more readily in warm water.
  • pH Levels: Being an acid, its ionization in basic conditions can also enhance solubility, allowing it to be more soluble in solutions where the pH is elevated.

In summary, when evaluating the solubility of 2-acetamidopentanedioic acid, it is essential to consider the solute-solvent interactions, especially through hydrogen bonding and the influence of temperature and pH. Such factors can lead to a higher degree of dissolution in suitable solvents.

Interesting facts

Interesting Facts about 2-Acetamidopentanedioic Acid

2-Acetamidopentanedioic acid, also known as 2-acetamido-1,2,3-propanetricarboxylic acid, is a fascinating compound that plays a significant role in organic and medicinal chemistry. Here are some enticing insights:

  • Biological Importance: This compound can be found in various biological systems and has implications in metabolic processes, making it relevant for research in biochemistry and pharmacology.
  • Synthetic Utility: Due to its structure, 2-acetamidopentanedioic acid serves as a versatile intermediate in the synthesis of various pharmaceutical agents and related compounds.
  • Functional Groups: The presence of both carboxylic acid and acetamido groups allows for interesting reactivity, enabling the compound to participate in diverse chemical reactions such as esterification and amide formation.
  • Structural Features: The symmetrical nature of the compound contributes to its stability and potency in various biological settings, particularly influencing enzyme activities.
  • Research Potential: Scientists are investigating its role in drug development, especially as a precursor to compounds that may exhibit anti-inflammatory or anti-cancer properties.

In summary, 2-acetamidopentanedioic acid is not just a compound with theoretical interest; it embodies a rich tapestry of applications and implications, making it a valuable subject of study for chemists and biochemists alike. As the saying in chemistry goes, "Every atom counts!" and in this case, each functional group holds unique potential.

Synonyms
2-acetamidopentanedioic acid
N-Acetyl-DL-glutamic acid
5817-08-3
N-acetylglutamic acid
ACEGLUMATE
DL-Acetylglutamic acid
Acetyl-DL-glutamic acid
acetylglutamate
Glutamic acid, N-acetyl-
N-Acetyl-DL-glutamicAcid
acetyl-glu
339072-10-5
MFCD00063195
Maybridge1_002521
2-acetamidopentanedioicacid
MLS002207281
DivK1c_001273
DL-Glutamic acid, N-acetyl-
SCHEMBL198970
CHEMBL2142890
HMS548K13
DTXSID00859595
CHEBI:172431
RFMMMVDNIPUKGG-UHFFFAOYSA-N
NSC10854
EINECS 227-388-6
BBL012280
BTB 13546
NSC 10854
NSC-10854
STK803143
AKOS005614049
AB02539
CS-W015958
FA41588
CDS1_000233
N-Acetylglutamic acid (Ac-DL-Glu-OH)
NCGC00094839-01
NCGC00094839-02
AS-59424
SMR001306797
SY017890
DB-053163
NS00002099
D95099
EN300-7397724
AG-205/32710033
AG-205/32710037
Q307661
102F8DF7-7489-46B2-80D2-B34561C2DF56