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Ketoprofen

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Identification
Molecular formula
C16H14O3
CAS number
22071-15-4
IUPAC name
2-acetoxy-2-phenyl-propanoic acid
State
State

Ketoprofen exists as a solid at room temperature.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
238.00
Boiling point (Kelvin)
511.15
General information
Molecular weight
254.28g/mol
Molar mass
254.2820g/mol
Density
1.1500g/cm3
Appearence

Ketoprofen is typically a white to off-white crystalline powder. It is odorless or may have a slight characteristic odor, and is slightly soluble in water, but freely soluble in ethanol and methanol.

Comment on solubility

Solubility of 2-acetoxy-2-phenyl-propanoic acid

2-acetoxy-2-phenyl-propanoic acid, commonly known for its distinctive molecular structure, exhibits varying levels of solubility in different solvents. Understanding its solubility is crucial for various applications, including pharmaceuticals and chemical synthesis.

Key Points about Solubility:

  • Polar Solvents: This compound is generally soluble in polar solvents such as water and methanol, which can stabilize interactions through hydrogen bonding.
  • Non-Polar Solvents: It displays lower solubility in non-polar solvents like hexane, owing to the hydrophobic nature of the phenyl group, which does not favor solvation.
  • Temperature Effects: Like many organic compounds, solubility tends to increase with temperature. Thus, warming the solvent can enhance the dissolution of 2-acetoxy-2-phenyl-propanoic acid.
  • pH Factor: The solubility may also be influenced by the pH of the solution. In more acidic or basic conditions, the ionization state of the carboxylic acid group can change, affecting its solubility.

In summary, 2-acetoxy-2-phenyl-propanoic acid demonstrates differential solubility that relies on its interaction with various solvents and environmental conditions. As stated, "the solubility prospects are intertwined with both polarity and the molecular structure." Understanding these factors is imperative for applications where this compound is utilized.

Interesting facts

Exploring 2-acetoxy-2-phenyl-propanoic acid

2-acetoxy-2-phenyl-propanoic acid, often referred to as a pharmaceutical compound, is notable for its medicinal properties and diverse applications. Here are some interesting facts about this intriguing compound:

  • Analgesic and Anti-inflammatory Properties: This compound is known for its effectiveness in reducing pain and inflammation, making it a valuable asset in pain management therapies.
  • Role in Organic Synthesis: It serves as an intermediate in the synthesis of more complex chemical entities, indicating its versatility in organic chemistry.
  • Mechanism of Action: The mechanism by which it exerts its effects involves the inhibition of specific biochemical pathways, which can lead to the relief of symptoms associated with various conditions.
  • Pharmaceutical Research: Continued studies on this compound are crucial, as scientists explore its potential uses and strive to enhance its efficacy and reduce side effects.
  • Regulatory Status: Understanding its regulatory status is essential for its development and clinical applications, especially in pharmaceutical markets.

Moreover, researchers are particularly interested in its structure-activity relationship (SAR), which examines how changes in its chemical structure could influence its biological activity. This compound's unique characteristics make it a fascinating subject of study for both chemists and medical researchers alike.

As noted by researchers, "The intersection of organic chemistry and pharmacology creates a rich opportunity for discovery and innovation." Whether in the lab or clinical settings, 2-acetoxy-2-phenyl-propanoic acid continues to shed light on the profound relationship between chemistry and health.

Synonyms
2-acetyloxy-2-phenylpropanoic acid
ALPHA-METHYL-ALPHA-ACETYLOXYBENZENEACETIC ACID
10487-92-0
SCHEMBL5322361
DTXSID30909254
2-(ACETYLOXY)-2-PHENYLPROPANOIC ACID