Ingenol mebutate | Solubility of Things

Identification

Molecular formula

C₂₅H₃₄O₆

CAS number

75567-37-2

IUPAC name

2-acetoxy-5,9-dimethyl-14-methylene-15-oxo-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid

State

Ingenol mebutate is a solid compound at room temperature. When used in pharmaceutical preparations, it may be suspended or dissolved for topical application.

Melting point (Celsius)

171.00

Melting point (Kelvin)

444.15

Boiling point (Celsius)

486.95

Boiling point (Kelvin)

760.15

General information

Molecular weight

430.53g/mol

Molar mass

430.5330g/mol

Density

1.2900g/cm³

Appearence

Ingenol mebutate typically appears as an off-white crystalline solid. It is known for its role in topical treatments and may come in pharmaceutical formulations that exhibit the characteristic appearance of creams or gels.

Comment on solubility

Solubility of 2-acetoxy-5,9-dimethyl-14-methylene-15-oxo-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid

The solubility characteristics of 2-acetoxy-5,9-dimethyl-14-methylene-15-oxo-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid (C₂₅H₃₄O₆) are influenced by its complex molecular structure, which features multiple functional groups. Here are some key points regarding its solubility:

Polarity: The presence of the carboxylic acid and acetoxy functional groups typically increases the polarity of the compound, which could enhance its solubility in polar solvents such as water.
Hydrophobic Nature: However, the large hydrophobic tetracyclic hydrocarbon structure can impede solubility in polar solvents, leading to a potentially low solubility overall.
Solvent Compatibility: This compound may exhibit better solubility in organic solvents like ethanol or methanol compared to water, following the principle "like dissolves like."
Temperature Effects: Solubility may also vary with temperature, where higher temperatures could potentially increase solubility in both polar and non-polar solvents.

Overall, the solubility of this compound can be described as moderate to low, strongly dependent on the solvent used, and highlighting the intriguing balance between its hydrophilic and hydrophobic characteristics.

Interesting facts

Interesting Facts about 2-acetoxy-5,9-dimethyl-14-methylene-15-oxo-tetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid

This unique chemical compound, known for its intricate structure and diverse functionalities, presents an exciting focus for both researchers and students in the field of organic chemistry. Here are some highlights that capture its significance:

Complex Structural Features: The compound is characterized by a tetracyclic framework, which contributes to its intriguing reactivity and potential applications in various fields.
Potential Biological Uses: Compounds with similar structures are often explored for their biological activity, including antibacterial and anti-inflammatory properties.
Synthetic Interest: The intricate nature of its synthesis garners attention within organic chemistry, as chemists seek to develop efficient pathways to create such complex molecules.
Functional Groups: The presence of both acetoxy and carboxylic acid functional groups suggests potential for various chemical reactivity, leading to opportunities for further chemical modifications.
Natural Product Inspiration: Many compounds inspired by natural products exhibit a range of pharmacological effects. Researchers may investigate this compound's potential as a lead compound in drug discovery.

As you delve into the world of this compound, consider the words of renowned chemist Linus Pauling: "Science is not only the study of nature; it is also a way of thinking about nature." Embracing this perspective may unlock new insights not only about this specific compound but also regarding its broader implications in chemistry and medicine.

The investigation of such fascinating structures helps deepen our understanding of molecular interactions and drives innovation in the creation of new materials and therapeutics!