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Trospium

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Identification
Molecular formula
C25H30ClNO3
CAS number
10405-02-4
IUPAC name
(2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium
State
State

At room temperature, Trospium chloride is in a solid state. In its pure form, it is a crystalline powder that is stable under standard conditions.

Melting point (Celsius)
242.50
Melting point (Kelvin)
515.60
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
427.98g/mol
Molar mass
427.9910g/mol
Density
1.1250g/cm3
Appearence

Trospium chloride appears as a white to off-white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the air. The compound is also noted for its solubility in water, which is a characteristic used in its pharmaceutical formulations.

Comment on solubility

Solubility of (2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium

The solubility of the compound (2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium is influenced by its unique chemical structure. Here are some key points to consider:

  • Polar vs. Non-Polar Regions: Due to the presence of acetoxy groups and a quaternary ammonium moiety, this compound can exhibit both polar and non-polar characteristics, which influences its solubility in various solvents.
  • Effects of Ionic Character: The dimethylammonium group contributes a positive charge, which typically increases solubility in polar solvents, especially water.
  • Hydrophilicity: Compounds with quaternary ammonium salts tend to be more soluble in aqueous solutions due to their ability to form hydrogen bonds with water molecules.
  • Influence of Molecular Weight: The large molecular size may hinder solubility in certain organic solvents, though the presence of functional groups may help to overcome this.
  • Critical Factors: Temperature, pH, and the nature of the solvent can significantly impact solubility. In general, an increase in temperature may improve solubility for many compounds.

In conclusion, while the specific solubility of (2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium may vary, it is likely to be better soluble in polar solvents, particularly water, compared to non-polar solvents. Understanding these solubility dynamics is crucial for applications in various fields, especially in pharmaceuticals where solubility can dictate bioavailability.

Interesting facts

Interesting Facts about (2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium

(2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium is a complex organic compound that belongs to a class of quaternary ammonium salts. These salts are often notable for their diverse applications in various fields, such as pharmaceuticals, where they can function as active ingredients or intermediates in drug synthesis.

Key Features:

  • Bioactivity: The compound's structure suggests it may possess biological activity, particularly owing to the presence of dimethylammonio groups that can interact with various biological membranes.
  • Synthesis: Its synthesis typically involves multiple steps, showcasing the intricate nature of organic synthesis, which can include acetylation and alkylation reactions.
  • Design Inspiration: The design of such compounds is often inspired by natural products, leading to innovative therapies and the development of drug delivery systems.

The compound stands out for its potential role in drug formulations due to its ability to enhance solubility and bioavailability of other pharmaceutical agents. Its quaternary structure aids in this respect by improving interactions with target sites within organisms.

Applications:

  • Used in antimicrobial agents for their ability to disrupt bacterial membranes.
  • Potential utility in cancer therapies as a targeted drug delivery system.
  • Explored for use in controlled release formulations, optimizing pharmacokinetics.

In summary, (2-acetoxycyclohexyl)methyl-[2-[4-[4-[2-[(2-acetoxycyclohexyl)methyl-dimethyl-ammonio]-2-oxo-ethyl]phenyl]phenyl]acetyl]-dimethyl-ammonium exemplifies the intricate and innovative world of organic chemistry. Its synthesis and potential applications remind us of the importance of chemical research in developing solutions to complex biological challenges.