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Choline chloride

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Identification
Molecular formula
C7H16ClNO2
CAS number
67-48-1
IUPAC name
2-acetoxyethyl(trimethyl)ammonium;chloride
State
State

At room temperature, choline chloride is generally found as a solid. Its hygroscopic nature often requires it to be stored in airtight containers to prevent moisture absorption.

Melting point (Celsius)
302.00
Melting point (Kelvin)
575.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
139.62g/mol
Molar mass
139.6230g/mol
Density
1.0470g/cm3
Appearence

Choline chloride is typically a white crystalline solid. It is hygroscopic, meaning it can absorb moisture from the air, and it often appears in solid form as free-flowing granules or powder.

Comment on solubility

Solubility of 2-acetoxyethyl(trimethyl)ammonium chloride

The solubility of 2-acetoxyethyl(trimethyl)ammonium chloride (C7H16ClNO2) is particularly noteworthy due to its ionic nature derived from the presence of the chloride ion. Here are some key points regarding its solubility:

  • Water Solubility: This compound is likely to be highly soluble in water owing to its ammonium group, which can engage in hydrogen bonding with water molecules.
  • Organic Solvents: Additionally, its acetoxy and alkyl groups suggest that it may also dissolve well in polar organic solvents, due to the presence of both hydrophilic and hydrophobic characteristics.
  • Temperature Influence: Solubility can be affected by temperature; generally, increasing temperature enhances solubility for solids in liquids.
  • pH Dependency: The solubility of such quaternary ammonium compounds can exhibit variability based on pH, as ionization states change, potentially affecting solubility in aqueous solutions.

It is important to note that while the compound is expected to be soluble, actual solubility will depend on various factors such as the presence of other solutes, and concentrations used in practical applications. Thus, understanding these dynamics is crucial for effective utilization.

Interesting facts

Interesting Facts about 2-acetoxyethyl(trimethyl)ammonium chloride

2-acetoxyethyl(trimethyl)ammonium chloride is a fascinating compound in the realm of organic chemistry. Here are some engaging insights about its properties and potential applications:

  • Quaternary Ammonium Compound: This compound is classified as a quaternary ammonium salt, which means it contains a positively charged nitrogen atom bonded to four organic groups. These types of compounds are well-known for their surface-active properties.
  • Biocidal Properties: Many quaternary ammonium compounds exhibit antimicrobial activity, making them useful in various disinfectants and antiseptics. They can effectively reduce bacterial growth, making them critical in healthcare and sanitation.
  • Versatile Applications: Due to its structure, 2-acetoxyethyl(trimethyl)ammonium chloride can be employed in a range of applications, including:
    • As a surfactant in personal care products
    • A potential ingredient in coatings and paints
    • In biochemical research as a modifying agent for biomolecules
  • Solvation Characteristics: The presence of both hydrophobic groups (the trimethylammonium part) and hydrophilic groups (the acetoxyethyl) makes this compound an interesting subject for studies on solvation and micelle formation, particularly in aqueous environments.
  • Structure-Activity Relationship (SAR): Understanding the relationship between molecular structure and biological activity can aid in the design of more effective antimicrobial agents. Studying compounds like 2-acetoxyethyl(trimethyl)ammonium chloride can provide insights into optimizing efficacy and minimizing toxicity.

In summary, 2-acetoxyethyl(trimethyl)ammonium chloride holds promise in fields ranging from surface chemistry to biochemistry. As researchers continue to explore its properties, the potential for novel applications and deeper understanding of its mechanisms only grows.

Synonyms
ACETYLCHOLINE CHLORIDE
60-31-1
Miochol
Acecoline
Acecholin
Chloroacetylcholine
Arterocoline
Ovisot
ACH chloride
Azetylcholinchlorid
2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
MIOCHOL-E
Acetylcholinium chloride
O-Acetylcholine chloride
2-Acetoxyethyltrimethylammonium chloride
Acetylcholine (chloride)
Choline acetate (ester) chloride
Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride
Acetylcholini chloridum
Cloruro de acetilcolina
Choline, chloride acetate
Acetylcholine hydrochloride
Acetilcolina cloruro
Acetilcolina cloruro [DCIT]
Chlorure d'acetylcholine
TL 1505
(2-Hydroxyethyl)trimethylammonium chloride acetate
AI3-51676
ACh (chloride)
Acetylcholini chloridum [INN-Latin]
EINECS 200-468-8
Chlorure d'acetylcholine [INN-French]
Cloruro de acetilcolina [INN-Spanish]
NSC-755845
UNII-AF73293C2R
CHEBI:2417
DTXSID5048978
AF73293C2R
Choline acetate (ester), chloride
MFCD00011698
60-31-1 (chloride)
Ammonium, (2-hydroxyethyl)trimethyl-, chloride, acetate
MLS000028640
DTXCID5028904
2-acetyloxy-N,N,N-trimethylethanaminium chloride
acetylcholine chloride for injection
NSC 755845
2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride (1:1)
SMR000059182
(2-Acetoxyethyl)trimethylammonium chloride
Acetylcholine chloride [USP:INN:BAN:JAN]
Acetylcholinechloride
Acetylcholini chloridum (INN-Latin)
ACETYLCHOLINE CHLORIDE (MART.)
ACETYLCHOLINE CHLORIDE [MART.]
Cloruro de acetilcolina (INN-Spanish)
ACETYLCHOLINE CHLORIDE (USP-RS)
ACETYLCHOLINE CHLORIDE [USP-RS]
CAS-60-31-1
Acetylcholine chloride (USP:INN:BAN:JAN)
ACETYLCHOLINE CHLORIDE (EP MONOGRAPH)
ACETYLCHOLINE CHLORIDE (USP IMPURITY)
ACETYLCHOLINE CHLORIDE [EP MONOGRAPH]
ACETYLCHOLINE CHLORIDE [USP IMPURITY]
ACETYLCHOLINE CHLORIDE (USP MONOGRAPH)
ACETYLCHOLINE CHLORIDE [USP MONOGRAPH]
NCGC00018123-05
vasil
Miochol E
Ach;ACh chloride
Miochol (TN)
Acetylcholine chloride [BAN:INN:JAN]
Acetylcholine chloride,
acetylcholinii chloridum
acetylcholinum chloratum
2-(trimethylamino)ethyl acetate, chloride
2-acetyloxyethyl(trimethyl)azanium;chloride
Opera_ID_1682
bmse000168
Acetylcholine Chloride1502
CHEMBL1184
REGID_for_CID_6060
SCHEMBL40885
SPECTRUM1500104
Acetylcholine Chloride Phenolic
HMS502C08
HY-B0282R
S01EB09
JUGOREOARAHOCO-UHFFFAOYSA-M
HMS1920A09
HMS2091G09
HMS2230B10
HMS3259J11
HMS3371L03
HMS3651K19
Pharmakon1600-01500104
ACETYLCHOLINE CHLORIDE [MI]
BCP31537
HY-B0282
Acetylcholine (chloride) (Standard)
ACETYLCHOLINE CHLORIDE [INN]
Tox21_113435
CCG-39125
NSC755845
ACETYLCHOLINE CHLORIDE [VANDF]
AKOS005111031
Tox21_113435_1
ACETYLCHOLINE CHLORIDE [WHO-DD]
FA47006
NC00643
Acetylcholine chloride (JP17/USP/INN)
NCGC00018123-07
NCGC00094577-01
NCGC00094577-02
NCGC00094577-03
DS-11397
ACETYLCHOLINE CHLORIDE [ORANGE BOOK]
DB-253713
A0084
NS00079143
SW220071-1
2-Acetoxy-N,N,N-trimethylethanaminium chloride
C08201
D00999
D81773
2-acetoxy-N,N,N-trimethylethan-1-aminium chloride
ACETYLCHOLINE CHLORIDE FOR INJECTION [JAN]
SR-01000003011
SR-01000003011-3
Q27105659
Ovisot; TL 1505; TL-1505; TL-1505; ACh chloride
Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride (1:1)
2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride;2-Acetoxyethyltrimethylammonium chloride;N-(2-Hydroxyethyl)trimethylammonium chlo ride acetate
200-468-8