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Thioglycolic acid

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Identification
Molecular formula
C2H4O2S
CAS number
68-11-1
IUPAC name
2-acetylsulfanylacetic acid
State
State

Thioglycolic acid is typically a liquid at room temperature.

Melting point (Celsius)
-16.00
Melting point (Kelvin)
257.15
Boiling point (Celsius)
96.00
Boiling point (Kelvin)
369.15
General information
Molecular weight
92.12g/mol
Molar mass
92.1200g/mol
Density
1.4210g/cm3
Appearence

Thioglycolic acid is a colorless liquid with a strong unpleasant odor. It is often found in its liquid form due to its low melting point. Upon exposure to air, it may acquire a pale yellow color.

Comment on solubility

Solubility of 2-acetylsulfanylacetic acid

2-acetylsulfanylacetic acid is known for its distinctive solubility characteristics, which can be influenced by various factors, including its molecular structure and the polarity of the solvent used. Generally, compounds like this one exhibit the following solubility traits:

  • Solubility in Water: Due to the presence of carboxylic acid groups, 2-acetylsulfanylacetic acid is likely to be moderately soluble in water. The polar nature of the carboxyl group enhances its ability to form hydrogen bonds with water.
  • Solubility in Organic Solvents: It tends to be more soluble in organic solvents like ethanol and methanol, where its non-polar acetyl group can interact favorably with the solvent molecules.
  • Temperature Effects: Increasing the temperature usually improves solubility for many compounds, and this may apply to 2-acetylsulfanylacetic acid as well. Temperature can disrupt intermolecular forces, thus increasing solute dissolution.
  • pH Influence: The solubility can also be affected by the pH of the solution. In a more acidic environment, the carboxylic acid group can remain protonated, whereas in basic conditions, it may deprotonate, creating a more soluble anionic form.

In conclusion, the solubility of 2-acetylsulfanylacetic acid is variable and context-dependent, making it crucial to consider solvent choice and environmental conditions when assessing its solubility.

Interesting facts

Interesting Facts about 2-Acetylsulfanylacetic Acid

2-Acetylsulfanylacetic acid, a fascinating thiol compound, offers intriguing insights into its chemical behavior and potential applications. Here are some notable aspects:

  • Unique Structure: This compound features a distinctive thiol group (-SH) paired with an acetyl substituent, which contributes to its chemical reactivity and versatility.
  • Biochemical Importance: Thiols play crucial roles in biological systems, often involved in enzyme function and protein structure stabilization. 2-Acetylsulfanylacetic acid could play a role in metabolic processes and biochemical pathways.
  • Potential in Synthesis: Due to its functional groups, it can serve as a valuable intermediate in the synthesis of more complex organic molecules, facilitating the creation of drugs and other bioactive compounds.
  • Aromatic Properties: Compounds containing thiol groups often exhibit interesting odor profiles, which can influence their application in flavor and fragrance industries.
  • Research Interest: Its unique properties make it a subject of interest in materials science and medicinal chemistry, where understanding its functionalities could lead to innovative drug designs.

As chemists delve deeper into the study of 2-acetylsulfanylacetic acid, they unveil its complexities and potential contributions to various fields, solidifying its importance in both academic research and practical applications.

Synonyms
1190-93-8
(Acetylthio)acetic acid
Acetic acid, 2-(acetylthio)-
S-Acetylthioglycolic acid
Mercaptoacetic acid acetate
Acetylmercaptoacetic acid
USAF EK-P-5430
Acetic acid, mercapto-, acetate
EINECS 214-725-7
BRN 1753984
ACETIC ACID, ACETYLMERCAPTO-
4-03-00-00610 (Beilstein Handbook Reference)
Acetic acid, mercapto-, acetate (8CI)
214-725-7
S-Acetylthioacetic acid
Acetic acid, (acetylthio)-
2-(Acetylthio)acetic acid
2-acetylsulfanylacetic acid
2-(acetylsulfanyl)acetic acid
MFCD00021763
S-Acetylmercaptoacetic Acid
2-(Acetylthio)aceticacid
acetylsulfanyl-acetic acid
Acetic acid,2-(acetylthio)-
SCHEMBL426229
3-Thiapentanoic acid, 4-oxo-
S-Acetyl-2-mercaptoacetic acid
CHEMBL3793817
DTXSID0061587
2-(Acetylthio)acetic acid, >=90%
AKOS006227915
AS-59425
SY013048
A2621
CS-0083252
NS00023834
H12044