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2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide

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Identification
Molecular formula
C11H9ClN2O5S
CAS number
57720-77-5
IUPAC name
2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide
State
State

At room temperature, 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide is in a solid state, typically appearing as a crystalline powder.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
315.72g/mol
Molar mass
315.7310g/mol
Density
1.5300g/cm3
Appearence

2-Allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide is typically a solid compound. It generally appears as a crystalline powder which may vary in color depending on impurities, but is often white to off-white.

Comment on solubility

Solubility of 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide

The solubility of 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide can be influenced by several factors such as temperature, solvent polarity, and molecular interactions. Generally, sulfonamide derivatives exhibit interesting solubility properties due to their polar sulfonamide groups and nonpolar hydrocarbon chains.

  • Solvent Polarity: This compound is likely to be more soluble in polar solvents due to the presence of the sulfonamide functional group. Solvents such as water or dimethyl sulfoxide (DMSO) may enhance solubility.
  • Temperature Impact: Increasing temperature might improve solubility as it typically increases kinetic energy, allowing for better interaction between the solute and solvent molecules.
  • Molecular Structure: The presence of the dioxo and chloro groups may also affect the hydrogen bonding capabilities of the molecule, potentially leading to varied solubility in different solvents.

It can be summarized that while specific solubility data may vary, understanding these influencing factors can provide insights into the solubility behavior of 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide. For practical applications, conducting solubility tests in various solvents under controlled conditions is highly recommended.

Interesting facts

Interesting Facts about 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide

2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide is a fascinating compound that belongs to the isoindoline family, which is renowned for its varied biological activities and applications in medicinal chemistry. Below are some compelling aspects of this compound:

  • Diverse Applications: This compound has shown potential in various fields, primarily as a pharmaceutical agent. Researchers are investigating its capabilities in targeting specific biological pathways, making it a candidate for future drug development.
  • Structure-Activity Relationship: The unique structure of 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide allows it to interact with biological systems in distinctive ways. The presence of the sulfonamide group is particularly noteworthy, as sulfonamides are widely recognized for their antibacterial properties.
  • Chloro Substituent: The 6-chloro substitution is crucial for the compound's reactivity and ability to form interactions with target proteins. Chlorine atoms can significantly influence the lipophilicity and electronic characteristics of compounds, which in turn affects their biological activity.
  • Potential as a Therapeutic Agent: Preliminary studies on similar compounds suggest that derivatives may exhibit anti-inflammatory and anticancer properties. As research progresses, the therapeutic potential of this compound may unravel new opportunities in drug design.
  • Innovative Synthesis: The synthetic methods to obtain this compound can involve various strategies, including multi-step organic synthesis techniques. This offers chemistry students and researchers a chance to explore advanced synthetic methodologies in organic chemistry.

Furthermore, the study of 2-allyl-6-chloro-1,3-dioxo-isoindoline-5-sulfonamide not only enriches our understanding of synthetic organic compounds but also highlights the importance of interdisciplinary research in addressing complex biological challenges. As chemists continue to explore this intriguing compound, who knows what groundbreaking discoveries await!

Synonyms
BRN 0431191
5-ISOINDOLINESULFONAMIDE, 2-ALLYL-6-CHLORO-1,3-DIOXO-
3862-01-9
DTXSID90191936
2-Allyl-6-chloro-1,3-dioxo-5-isoindolinesulfonamide
1H-Isoindole-5-sulfonamide, 6-chloro-2,3-dihydro-1,3-dioxo-2-(2-propenyl)-
5-22-07-00597 (Beilstein Handbook Reference)
DTXCID30114427