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2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide

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Identification
Molecular formula
C14H19ClN2O2
CAS number
2163-11-9
IUPAC name
2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide
State
State

The compound is typically in a solid state at room temperature. It exists as a stable crystalline powder, which is common for many organic compounds containing benzamide groups. The compound is handled in solid form in chemical processes and formulations.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
281.78g/mol
Molar mass
281.7770g/mol
Density
1.1500g/cm3
Appearence

The compound appears as a solid with crystalline properties. It is typically white or off-white in color and may have a mild odor due to the allyloxy group. The compound’s solid state contributes to its stable shelf life when kept under appropriate conditions of temperature and light exposure.

Comment on solubility

Solubility of 2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide

The solubility of 2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide in different solvents can be influenced by various factors, including its structural characteristics and the presence of functional groups. Here are key points to consider:

  • Polarity: The molecule contains both polar and non-polar regions due to its alkyl and aryl components. This mixture often results in moderate solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The amide group can participate in hydrogen bonding, potentially enhancing solubility in polar solvents.
  • Hydrophobic Regions: The allyloxy and chloro substituents may introduce hydrophobic character, which could limit solubility in very polar solvents.
  • Solvent Compatibility: It may exhibit better solubility in organic solvents like ethanol or acetone than in water.

In summary, the solubility characteristics of 2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide can best be described as moderate and dependent on the solvent's polarity and capability to stabilize different molecular interactions.

Interesting facts

Interesting Facts about 2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide

2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide, a fascinating compound in the realm of medicinal chemistry, is known for its diverse applications and intriguing properties. Here are some engaging insights:

  • Pharmaceutical Potential: This compound is a derivative of benzamide, which is a vital framework in medicinal chemistry. Benzamides are often explored for their potential as therapeutic agents, particularly in areas such as anti-cancer and anti-inflammatory research.
  • Structural Diversity: The presence of both allyloxy and dimethylamino groups contributes to the compound's unique structure, which may affect its biological activity. This structural diversity often leads to enhanced bioavailability and improved pharmacokinetics in drug development.
  • Chlorination Effects: The chlorination at the 4-position of the benzamide ring can modify the compound's reactivity and interaction with biological targets. This substitution pattern is often found in compounds with significant biological activity.
  • Research Interest: The compound has captured the interest of researchers studying receptor interactions and dose-dependent responses, which are crucial for the design of new therapeutics.
  • Analytical Techniques: Scientists often use techniques such as NMR spectroscopy and mass spectrometry to analyze and characterize such complex molecules, ensuring their purity and understanding their pharmacological properties.

In summary, 2-allyloxy-4-chloro-N-[2-(dimethylamino)ethyl]benzamide is more than just a chemical compound; it represents a key area of research within the field of medicinal chemistry, offering potential pathways for the development of innovative therapeutic agents. As the study of this compound progresses, it may very well lead to breakthroughs in drug discovery and development!

Synonyms
264CD
10330-67-3
BENZAMIDE, 2-(ALLYLOXY)-4-CHLORO-N-(2-(DIMETHYLAMINO)ETHYL)-
2-(Allyloxy)-4-chloro-N-(2-(dimethylamino)ethyl)benzamide
DTXSID10145774
DTXCID7068265
4-chloro-N-[2-(dimethylamino)ethyl]-2-prop-2-enoxybenzamide