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2-Amino-1-(3,4,5-trimethoxyphenyl)ethanol

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Identification
Molecular formula
C11H17NO4
CAS number
2070-10-4
IUPAC name
2-amino-1-(3,4,5-trimethoxyphenyl)ethanol
State
State
This compound is typically a solid at room temperature, existing as a crystalline powder.
Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
391.50
Boiling point (Kelvin)
664.65
General information
Molecular weight
213.23g/mol
Molar mass
213.2320g/mol
Density
1.2760g/cm3
Appearence
2-Amino-1-(3,4,5-trimethoxyphenyl)ethanol appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol

The solubility of 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol can be quite intriguing, especially when considering its unique structure that contains methoxy groups which can influence its behavior in solvents. Here's a breakdown of its solubility characteristics:

  • Solvent Compatibility: This compound is likely to be soluble in polar solvents like water and dimethyl sulfoxide (DMSO), due to the presence of the amino group which can engage in hydrogen bonding.
  • Hydrophobic Interactions: The trimethoxyphenyl component adds hydrophobic characteristics that might limit solubility in very nonpolar solvents.
  • pH Dependency: The solubility may be pH-dependent, as the amino group can become protonated in acidic conditions, potentially increasing its solubility in such environments.
  • Temperature Effects: Typically, an increase in temperature could enhance solubility due to increased kinetic energy allowing more interactions with the solvent.

In summary, the solubility of 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol fits a nuanced profile influenced by its specific functional groups. Understanding the balance between its polar and nonpolar aspects is key to predicting its behavior in solution.

Interesting facts

Interesting Facts about 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol

2-amino-1-(3,4,5-trimethoxyphenyl)ethanol, often referred to as a neurotransmitter precursor, possesses some fascinating properties and functions that intrigue both chemists and pharmacologists. Here are some noteworthy aspects:

  • Structural Diversity: This compound features an amino group attached to a phenyl ring that is further substituted with three methoxy groups. This structural diversity allows it to participate in various chemical reactions.
  • Biological Significance: 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol is known to be involved in the biosynthesis of important neurotransmitters, leading to interest in its potential neuroprotective effects.
  • Potential Applications: Research has indicated this compound may help in the treatment of mood disorders, making it a subject of investigation for new antidepressant therapies.
  • Natural Occurrence: Some derivatives of this compound can be found in certain plants, showcasing nature's intricate chemistry and its role in traditional remedies.
  • Research Frontiers: Ongoing studies on this compound aim to uncover more about its mechanism of action at the molecular level, potentially leading to breakthroughs in mental health treatment and drug design.

As a compound with multifaceted properties and significant implications in biological systems, 2-amino-1-(3,4,5-trimethoxyphenyl)ethanol exemplifies the intersection of chemistry and health. Its exploration may lead to new therapeutic strategies and enhance our understanding of neurotransmission.

Synonyms
2-amino-1-(3,4,5-trimethoxyphenyl)ethanol
13079-18-0
2-amino-1-(3,4,5-trimethoxyphenyl)ethan-1-ol
SCHEMBL7927945
BHURFCFBOPXSCN-UHFFFAOYSA-N
CHEBI:125361
MFCD00798886
SY487117
EN300-1852378
1-(1-hydroxy-2-aminoethyl)-3,4,5-trimethoxy benzene
BRD-A06779035-001-01-7
Q27215715