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Chloroacetoacetone

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Identification
Molecular formula
C8H8ClNO
CAS number
42084-44-6
IUPAC name
2-amino-1-(4-chlorophenyl)ethanone
State
State

At room temperature, 2-amino-1-(4-chlorophenyl)ethanone is typically found in the solid state. It is stable under normal conditions and can be handled safely with standard precautions for chemical solids.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
256.00
Boiling point (Kelvin)
529.15
General information
Molecular weight
171.61g/mol
Molar mass
171.6090g/mol
Density
1.2490g/cm3
Appearence

2-Amino-1-(4-chlorophenyl)ethanone appears as a crystalline solid. The compound is typically colorless, but it may appear as a white to light-yellow crystalline powder when impure or exposed to various conditions.

Comment on solubility

Solubility of 2-amino-1-(4-chlorophenyl)ethanone

The solubility of 2-amino-1-(4-chlorophenyl)ethanone is influenced by several factors, primarily its molecular structure and interactions with solvents. Understanding its solubility characteristics can reveal important insights:

  • Solvent Polarity: The compound is expected to be more soluble in polar solvents such as water or alcohols due to its amino group, which can engage in hydrogen bonding.
  • Hydrogen Bonding: The amino group (-NH2) enhances solubility as it can form hydrogen bonds with solvent molecules, making it more likely to dissolve in polar environments.
  • Hydrophobic Interactions: The bulky 4-chlorophenyl group may reduce solubility in very polar solvents. Thus, a balance between the polar and non-polar characteristics must be considered.

In summary, the solubility of 2-amino-1-(4-chlorophenyl)ethanone is likely to be moderate to high in polar solvents due to the presence of the amino functional group, although interactions with the chlorophenyl moiety may present some solubility challenges.

Understanding these solubility dynamics may aid in various practical applications, including drug formulation and synthetic pathways.

Interesting facts

Interesting Facts about 2-Amino-1-(4-chlorophenyl)ethanone

2-Amino-1-(4-chlorophenyl)ethanone, a fascinating compound in the realm of organic chemistry, showcases a unique structure that has drawn the attention of researchers and chemists alike. Here are some compelling points about this compound:

  • Structural Characteristics: This compound features an amine group and a carbonyl functionality, contributing to its interesting reactivity and potential applications.
  • Biological Relevance: The presence of the 4-chlorophenyl moiety hints at potential bioactivity. Compounds like this are often studied for their pharmacological properties, leading to discoveries in medicinal chemistry.
  • Reaction Versatility: As an aminoketone, it can participate in a range of chemical reactions, including nucleophilic additions and electrophilic substitutions, making it valuable in synthetic organic pathways.
  • Historical Significance: Compounds with similar structures have been central in the development of drugs and therapeutic agents, especially in the fields of analgesics and anti-inflammatory medications.

Furthermore, the study of 2-amino-1-(4-chlorophenyl)ethanone contributes to our understanding of how small modifications in molecular structure can lead to significant changes in properties and functions. As researchers continue to explore its applications, we may uncover novel uses that could impact fields ranging from pharmaceuticals to agrochemicals.

In summary, the unique features of 2-amino-1-(4-chlorophenyl)ethanone not only highlight the beauty of organic chemistry but also emphasize the importance of such compounds in real-world applications.

Synonyms
2-amino-4'-chloroacetophenone
7644-03-3
2-amino-1-(4-chlorophenyl)ethanone
2-amino-1-(4-chlorophenyl)ethan-1-one
Ethanone, 2-amino-1-(4-chlorophenyl)-
Ethanone, 2-amino-1-(4-chlorophenyl)-, hydrochloride
MFCD01123946
2-amino-1-(4-chlorophenyl)-1-ethanone
Maybridge1_000938
SCHEMBL310686
2-Amino-4''-chloroacetophenone
ALBB-024415
STK664154
AKOS000285089
CCG-233928
GS-3558
BP-13116
1-Ethanone, 2-amino-1-(4-chlorophenyl)-
DB-020360
CS-0100867
EN300-40583
F2169-1086