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Fluoxetine Hydrochloride

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Identification
Molecular formula
C17H19ClFNO
CAS number
56296-78-7
IUPAC name
2-amino-1-(4-fluorophenyl)ethanol;hydrochloride
State
State

At room temperature, fluoxetine hydrochloride is typically in a solid state. The compound is generally stable under standard temperature and pressure conditions.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
206.00
Boiling point (Kelvin)
479.15
General information
Molecular weight
309.33g/mol
Molar mass
309.3310g/mol
Density
1.2300g/cm3
Appearence

Fluoxetine hydrochloride typically appears as a white to off-white crystalline solid. It is commonly available in powdered form for use in pharmaceutical preparations. The material may be hygroscopic, absorbing moisture from the environment, which should be considered during storage.

Comment on solubility

Solubility of 2-amino-1-(4-fluorophenyl)ethanol;hydrochloride

The solubility of 2-amino-1-(4-fluorophenyl)ethanol;hydrochloride is an important characteristic that can influence its functionality and application in various chemical contexts. This compound, classified as a hydrochloride salt, typically exhibits high solubility in polar solvents such as water. Here are some key points regarding its solubility:

  • Hydrophilicity: The presence of amine and hydroxyl functional groups enhances its interaction with water molecules, leading to increased solubility.
  • Temperature Dependence: As is common with many salts, the solubility of 2-amino-1-(4-fluorophenyl)ethanol;hydrochloride may increase with rising temperature.
  • pH Influence: Changes in pH can affect the ionization state of the amine group, thus modifying solubility. Generally, more acidic conditions can produce greater solubility for ammonium salts.

In summary, one might say that the solubility properties of this compound are largely dictated by its ionic nature and the overall presence of polar functional groups, making it readily soluble in most aqueous environments. Hence, understanding these characteristics is crucial for applications in pharmaceuticals and chemical synthesis.

Interesting facts

Exploring 2-Amino-1-(4-fluorophenyl)ethanol Hydrochloride

2-Amino-1-(4-fluorophenyl)ethanol hydrochloride is a fascinating compound with notable applications in the field of medicinal chemistry. Here are some intriguing facts about this compound:

  • Pharmaceutical Relevance: This compound is often investigated for its potential role as a pharmaceutical agent, especially in the treatment of various neuropsychiatric disorders.
  • Structural Insights: The presence of the 4-fluorophenyl group enhances the compound's lipophilicity, which may improve its ability to cross biological membranes.
  • Bioactivity: Its amino group is crucial for forming hydrogen bonds, thereby increasing its interaction with biological targets. This characteristic can enhance the drug's efficacy.
  • Synthesis: The preparation of 2-amino-1-(4-fluorophenyl)ethanol can involve various synthetic routes, often highlighting the creativity and ingenuity of organic chemists.
  • Impact of Fluorine: The introduction of fluorine not only alters the electronic properties but may also affect the pharmacokinetics of the molecule, making it a subject of interest for drug development.

This compound exemplifies the interplay between chemical structure and biological activity, showcasing how even subtle modifications can lead to significant changes in a compound's properties and applications. As researchers continue to explore its potential, compounds like 2-amino-1-(4-fluorophenyl)ethanol hydrochloride pave the way for advancements in medicine.

Synonyms
403-28-1
2-amino-1-(4-fluorophenyl)ethanol hydrochloride
2-HYDROXY-2-(4-FLUOROPHENYL)ETHYLAMINE HYDROCHLORIDE
2-Amino-1-(4-fluoro-phenyl)-ethanol hydrochloride
2-amino-1-(4-fluorophenyl)ethanol;hydrochloride
2-Amino-1-(4-fluorophenyl)ethan-1-ol hydrochloride
2-Hydroxy-2-(4-fluorophenyl)ethylamine, HCl
2-Amino-1-(4-fluorophenyl)ethan-1-olhydrochloride
2-HYDROXY-2-(4-FLUOROPHENYL)ETHYLAMINE HCL
alpha-(Aminomethyl)-4-fluorobenzyl alcohol hydrochloride
alpha-Aminomethyl-p-fluorobenzyl alcohol hydrochloride
AR2888
MFCD01664398
2-Amino-1-(4-fluorophenyl)ethanol HCl
BENZYL ALCOHOL, alpha-AMINOMETHYL-p-FLUORO-, HYDROCHLORIDE
SCHEMBL19666947
Benzenemethanol, a-(aminomethyl)-4-fluoro-, hydrochloride
DTXSID20960738
KNB20465
KXB19825
MFCD28064006
AKOS016010389
AS-45470
SY163381
CS-0170976
EN300-296372
2-Amino-1-(4-fluorophenyl)ethan-1-ol--hydrogen chloride (1/1)