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Ceramide III

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Identification
Molecular formula
C18H37NO2
CAS number
103051-63-4
IUPAC name
2-amino-1-hydroxy-octadecan-3-one
State
State
Solid at room temperature.
Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.15
General information
Molecular weight
299.49g/mol
Molar mass
301.5000g/mol
Density
1.0500g/cm3
Appearence

Ceramide III is a waxy solid, typically appearing as an off-white or pale yellow powder.

Comment on solubility

Solubility of 2-amino-1-hydroxy-octadecan-3-one

The solubility of 2-amino-1-hydroxy-octadecan-3-one (C18H37NO2), a fatty acid derivative, is influenced by several factors:

  • Hydrophobicity: Due to its long hydrocarbon chain, this compound exhibits significant hydrophobic character, which may reduce its solubility in polar solvents.
  • Hydrophilicity of Functional Groups: The presence of amino (–NH2) and hydroxy (–OH) groups can enhance solubility in polar solvents like water, particularly when hydrogen bonding is facilitated.
  • Temperature Dependency: Solubility often increases with temperature, allowing for greater dissolution in various solvents as kinetic energy promotes interaction.
  • pH Sensitivity: The solubility may vary with pH, as the ionization state of the amino group can affect its compatibility with solvents.

In summary, the solubility of 2-amino-1-hydroxy-octadecan-3-one can be characterized as moderate, primarily influenced by its dual nature of hydrophobic and hydrophilic properties. In practical applications, one might consider various solvents for adequate solubilization, keeping in mind the balance between environmental conditions and solvent type used.

Interesting facts

Interesting Facts about 2-amino-1-hydroxy-octadecan-3-one

2-amino-1-hydroxy-octadecan-3-one is a fascinating compound with unique properties and applications. Here are some intriguing aspects of this chemical:

  • Biological Significance: This compound serves as a key structural component in various biochemical pathways, possibly acting as a precursor to important biological molecules.
  • Potential Therapeutic Uses: Due to its amino and hydroxy functional groups, 2-amino-1-hydroxy-octadecan-3-one has been explored for potential applications in medicinal chemistry, especially in drug development.
  • Nature of Interaction: The presence of both amino and hydroxy groups enhances the compound's ability to form hydrogen bonds, potentially increasing its solubility in biological systems.
  • Fatty Acid Derivative: As an 18-carbon long-chain molecule, it is classified among fatty acid derivatives, making it relevant in studies focused on lipid chemistry and metabolism.

As quoted by renowned chemists, “The intricacies of molecular interactions can lead to groundbreaking discoveries,” and 2-amino-1-hydroxy-octadecan-3-one is a prime example of how chemistry can intersect with biology to unveil new insights.

In summary, the compound holds promise not only in the realms of organic chemistry but also in addressing health-related issues, making its study an interesting venture for both students and professionals alike.

Synonyms
2-amino-1-hydroxyoctadecan-3-one
16105-69-4
1-Hydroxy-2-amino-3-oxo-octadecane
Ketodihydrosphingosine
CHEBI:46966
2-amino-1-hydroxy-3-octadecanone
3-Octadecanone, 2-amino-1-hydroxy-
2-AMINO-1-HYDROXY-OCTADECAN-3-ONE
D,L-3-Dehydrosphinganin
3-keto-dihydrosphingosine
SCHEMBL678575
DTXSID80864662
2-amino-1-hydroxyoctadecane-3-one
TAA94428
(+-)-isomer of ketodihydrosphingosine
PD025531
NS00122772
3-KETO-DIHYDROSPHINGOSINE HYDROCHLORIDE
Q27120739