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2-Amino-6-mercaptopurine

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Identification
Molecular formula
C6H6N4S
CAS number
160-07-6
IUPAC name
2-amino-1-methyl-purine-6-thiol
State
State

At room temperature, 2-amino-6-mercaptopurine is in a solid state. It is typically crystalline and retains its form unless exposed to conditions where it may dissolve or decompose.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
506.70
Boiling point (Kelvin)
779.90
General information
Molecular weight
167.20g/mol
Molar mass
167.1980g/mol
Density
2.0210g/cm3
Appearence

2-Amino-6-mercaptopurine typically appears as a crystalline solid with a yellowish appearance. It may vary slightly in color depending on the purity and form in which it is isolated.

Comment on solubility

Solubility of 2-amino-1-methyl-purine-6-thiol

2-amino-1-methyl-purine-6-thiol, with its complex structure, presents interesting solubility characteristics. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound tends to be soluble in polar solvents such as water and alcohols due to the presence of amine and thiol functional groups.
  • Dissolution Behavior: The solubility can be influenced by factors including temperature and pH, highlighting the need for careful experimentation in various conditions.
  • Concentration Dependent: As concentrations increase, the solubility may reach a saturation point where the compound may precipitate out of solution.
  • Hydrogen Bonding: The ability of the thiol and amino groups to form hydrogen bonds plays a significant role in promoting solubility in aqueous solutions.

Overall, while 2-amino-1-methyl-purine-6-thiol exhibits favorable solubility in specific conditions, it is essential to evaluate its properties in the context of the intended application. Studying solubility behaviors is crucial for further applications, such as in pharmaceuticals where bioavailability is key.

Interesting facts

Interesting Facts About 2-Amino-1-methyl-purine-6-thiol

2-Amino-1-methyl-purine-6-thiol, often abbreviated as AMPT, is a fascinating compound that plays a significant role in the study of biochemistry and pharmacology. It is recognized as an important purine derivative, which makes it an integral part of the nucleic acid structure that underpins genetic information.

Key Characteristics

  • Biochemical Relevance: AMPT has been studied for its function as a substrate in enzyme reactions and its potential impact on metabolic pathways.
  • Research Applications: Its derivatives and analogs are often investigated for their therapeutic applications, particularly in the treatment of neurological disorders.
  • Structural Significance: The presence of the thiol group (-SH) in AMPT is critical, as it can participate in redox reactions and contribute to the formation of disulfide bonds, impacting protein structure and function.

Potential Uses

The potential uses of 2-amino-1-methyl-purine-6-thiol extend into various fields. Some notable applications include:

  • As a component in drug formulations.
  • In molecular biology for the study of nucleic acid modifications.
  • As a target in the development of anticancer agents due to its effects on cell proliferation.

Quote from Chemistry Literature

"Understanding the biochemical properties of purine derivatives opens doors to novel therapeutic strategies." - A reference from a recent study on purine analogs.

This compound exemplifies the interplay between structure and function in biochemistry. By exploring the multifaceted roles of 2-amino-1-methyl-purine-6-thiol, scientists can gain insights into the intricate molecular frameworks that govern life.