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2-Amino-1-phenylbutan-1-ol

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Identification
Molecular formula
C10H15NO
CAS number
106-51-4
IUPAC name
2-amino-1-phenyl-butan-1-ol
State
State

At room temperature, 2-amino-1-phenylbutan-1-ol is typically in a solid state, often observed as crystalline or powdery in form.

Melting point (Celsius)
74.00
Melting point (Kelvin)
347.00
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.00
General information
Molecular weight
165.23g/mol
Molar mass
165.2330g/mol
Density
1.0370g/cm3
Appearence

2-Amino-1-phenylbutan-1-ol typically appears as a colorless or pale yellow crystalline solid. It can also be found as a crystalline powder. In some cases, slight variations in color may be observed due to impurities or different conditions of synthesis and storage.

Comment on solubility

Solubility of 2-amino-1-phenyl-butan-1-ol

The solubility of 2-amino-1-phenyl-butan-1-ol can be influenced by various factors, particularly due to its functional groups. The presence of the amino group (-NH2) typically enhances solubility in polar solvents, while the phenyl group can introduce hydrophobic characteristics that may limit solubility in non-polar environments.

Key Points Regarding Solubility:

  • Polar Solvents: The compound is likely to be soluble in polar solvents such as water and alcohols, owing to the ability of the amino group to engage in hydrogen bonding.
  • Non-Polar Solvents: Solubility in non-polar solvents may be restricted because the aromatic phenyl group does not favorably interact with such environments.
  • pH Dependency: The solubility can also change with pH, as protonation of the amino group can attract more solvent molecules, increasing solubility.

To summarize, the solubility of 2-amino-1-phenyl-butan-1-ol varies based on the solvent environment, making it crucial to consider the specific conditions when predicting its solubility behavior.

Interesting facts

Interesting Facts About 2-Amino-1-phenyl-butan-1-ol

2-Amino-1-phenyl-butan-1-ol, often abbreviated as APB, is a fascinating compound primarily known for its intricate structure and diverse applications in organic chemistry.

Key Characteristics

  • Structure: This compound features an amino group attached to a butanol backbone, along with a phenyl group. This unique structure imparts it specific reactivity profiles and potential utility in synthetic chemistry.
  • Steric Hindrance: The presence of bulky phenyl and amino groups creates interesting steric effects that influence its chemical behavior, making it a valuable subject of study in stereochemistry.
  • Precursor in Synthesis: It serves as a crucial intermediate in the synthesis of various pharmaceuticals and chemical compounds, showcasing its importance in medicinal chemistry.

Applications

2-Amino-1-phenyl-butan-1-ol is not merely of academic interest; it also finds its applications in various fields:

  • Pharmaceutical Development: It is used in the design of compounds that may have therapeutic effects.
  • Research Tool: In biochemical research, it can serve as a model compound to study the interactions of amines with biological systems.
  • Organic Synthesis: Its ability to participate in diverse reaction mechanisms makes it a staple in the toolkit of synthetic chemists.

Fun Fact

In the world of chemistry, compounds like APB are often termed as chiral. This means they exist in forms that are mirror images of each other, which is critical in the context of drug function, as different enantiomers can exhibit vastly different biological activities.

Overall, 2-amino-1-phenyl-butan-1-ol not only enriches the landscape of organic compounds but also serves as a reminder of the intricate relationship between chemical structure and functionality.

Synonyms
2-amino-1-phenylbutan-1-ol
DTXSID40871918
DTXCID20819530
835-342-7
5897-76-7
2-AMINO-1-PHENYL-BUTANOL
alpha-(alpha-Aminopropyl)benzyl alcohol
1-Butanol,2-amino-1-phenyl
2-Amino-1-phenyl-1-butanol
USAF CS-7
1-Phenyl-1-hydroxy-2-amino-n-butane
1-Butanol, 2-amino-1-phenyl-
beta-Amino-alpha-phenylbutyl alcohol
alpha-(1-Aminopropyl)benzenemethanol
NSC 41764
UNII-S8TT5K3C8Y
Benzenemethanol, alpha-(1-aminopropyl)-
Benzenemethanol, .alpha.-(1-aminopropyl)-
Benzyl alcohol, .alpha.-(1-aminopropyl)-
BENZYL ALCOHOL, alpha-(1-AMINOPROPYL)-
S8TT5K3C8Y
SCHEMBL2838848
FAA89776
NSC41764
NSC-41764
.alpha.-(.alpha.-Aminopropyl)benzyl alcohol
EN300-145308