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2-Amino-4-hydroxybenzothiazole

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Identification
Molecular formula
C7H6N2OS
CAS number
1477-59-2
IUPAC name
2-amino-1,3-benzothiazol-4-ol
State
State

At room temperature, 2-Amino-4-hydroxybenzothiazole is typically in a solid state, indicating it's stable under normal conditions. The solid state allows it to be handled and used in a variety of chemical processes, especially in research and industrial applications.

Melting point (Celsius)
273.00
Melting point (Kelvin)
546.00
Boiling point (Celsius)
356.50
Boiling point (Kelvin)
629.70
General information
Molecular weight
166.21g/mol
Molar mass
166.2080g/mol
Density
1.4615g/cm3
Appearence

2-Amino-4-hydroxybenzothiazole appears as a grey to light brown solid. It typically crystallizes as a powder or fine crystal form. The appearance may vary slightly depending on purity and specific crystallization method.

Comment on solubility

Solubility of 2-amino-1,3-benzothiazol-4-ol

2-amino-1,3-benzothiazol-4-ol, often referred to as an important organic compound, exhibits unique solubility characteristics that are noteworthy:

  • Solubility in Water: This compound is generally considered to be moderately soluble in water. The presence of the amino group (-NH2) and the hydroxyl group (-OH) significantly enhances its ability to interact with water molecules through hydrogen bonding.
  • Solubility in Organic Solvents: In addition to water, 2-amino-1,3-benzothiazol-4-ol shows high solubility in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). This versatility makes it a valuable compound in various chemical reactions and synthesis processes.
  • Influence of pH: The solubility may vary with pH. Under acidic conditions, the solubility tends to increase due to the protonation of the amino group, facilitating interactions with the solvent.

Overall, the solubility profile of 2-amino-1,3-benzothiazol-4-ol makes it a suitable candidate for applications in organic synthesis, analytical chemistry, and pharmaceuticals. As always, it is essential to consider the solubility when planning experiments or reactions involving this compound.

Interesting facts

Interesting Facts about 2-amino-1,3-benzothiazol-4-ol

2-amino-1,3-benzothiazol-4-ol is a fascinating compound with a variety of intriguing properties and applications. Here are some noteworthy aspects:

  • Structure and Fusion: The compound features a benzothiazole core, which is a bicyclic structure containing both a benzene ring and a thiazole ring. This unique combination imparts distinct chemical reactivity.
  • Biological Activity: 2-amino-1,3-benzothiazol-4-ol has garnered attention in medicinal chemistry for its potential therapeutic properties. It has been investigated for its anti-inflammatory, antitumor, and antimicrobial activities.
  • Fluorescent Properties: The compound exhibits interesting fluorescence characteristics, making it useful in various imaging techniques and potentially applicable in developing new fluorescent probes.
  • Analytical Uses: Given its stability and distinct spectral properties, 2-amino-1,3-benzothiazol-4-ol has importance in analytical chemistry. It can be utilized in the development of analytical methods for detecting metal ions.
  • Cross-Discipline Relevance: This compound finds relevance not just in chemistry but also in fields such as biochemistry and materials science. Its unique properties can contribute to advancements in various research areas.

In summary, 2-amino-1,3-benzothiazol-4-ol is more than just a chemical name. It is a bridge between synthetic chemistry and practical applications in biology and materials science. As researchers delve deeper into its properties, more exciting discoveries are expected to emerge!

Synonyms
2-Amino-4-hydroxybenzothiazole
7471-03-6
4-Benzothiazolol, 2-amino-
2-amino-1,3-benzothiazol-4-ol
2-aminobenzothiazol-4-ol
4-Hydroxy-2-aminobenzothiazole
OBI166S5VM
BENZOTHIAZOLE, 2-AMINO-4-HYDROXY-
UNII-OBI166S5VM
NSC 403535
NSC-403535
BRN 0136771
2-AMINO-4-BENZOTHIAZOLOL
DTXSID20225692
4-BENZOTHIAZOLOL, 2-AMINO
4-27-00-05445 (Beilstein Handbook Reference)
DTXCID50148183
4-Benzothiazolol, 2-amino-(9CI)
2-aminobenzo[d]thiazol-4-ol
2-Amino-benzothiazol-4-ol
MFCD00160060
CHEMBL1269497
NSC403535
2-Amino-4-hydroxy-1,3-benzothiazole
Oprea1_629632
SCHEMBL74065
2-Amino-4-hydroxy-benzthiazol
4-hydroxybenzo[d]thiazol-2-amine
PFQJPSASUCHKRO-UHFFFAOYSA-N
WLN: T56 BN DSJ CZ IQ
2-azanyl-1,3-benzothiazol-4-ol
STR08126
BDBM50339018
AKOS001592678
AC-6357
CS-W006232
SB18595
SS-3440
SY030134
2-amino-4-hydroxybenzothiazole, AldrichCPR
DB-005936
DB-227267
A3001
EU-0067153
NS00037651
A838203
SR-01000391909
SR-01000391909-1
Q27285555