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Phenylpropanolamine

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Identification
Molecular formula
C9H13NO
CAS number
14838-15-4
IUPAC name
2-amino-2-methyl-1-phenyl-propan-1-ol
State
State

Phenylpropanolamine is typically in a solid state at room temperature, appearing as a white crystalline powder.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
171.00
Boiling point (Kelvin)
444.15
General information
Molecular weight
151.21g/mol
Molar mass
151.2110g/mol
Density
1.1108g/cm3
Appearence

Phenylpropanolamine is typically a white crystalline powder.

Comment on solubility

Solubility of 2-amino-2-methyl-1-phenyl-propan-1-ol

2-amino-2-methyl-1-phenyl-propan-1-ol, with its intriguing structure, exhibits characteristics that influence its solubility. Here are some key aspects to consider:

  • Polarity: The presence of the amino group (-NH2) increases the polarity of the compound, leading to enhanced solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds makes it more soluble in water and other polar solvents. This property is crucial for its interactions in biological systems.
  • Solubility in Organic Solvents: It can also dissolve in various organic solvents, particularly those that are polar, such as alcohols and dimethyl sulfoxide (DMSO).
  • Temperature Effects: Temperature can influence solubility; generally, increasing temperature tends to enhance solubility in most solvents due to increased molecular motion.

Overall, the unique functional groups in 2-amino-2-methyl-1-phenyl-propan-1-ol contribute significantly to its solubility profile, allowing it to interact effectively in various environments. As with many compounds, solubility plays a crucial role in its practical applications and biological relevance.

Interesting facts

Interesting Facts about 2-amino-2-methyl-1-phenyl-propan-1-ol

2-amino-2-methyl-1-phenyl-propan-1-ol, commonly known as a derivative of phenylpropanolamine, is an intriguing compound due to its application in various fields of research and its unique structural characteristics.

Key Attributes

  • Chiral Compound: This compound possesses a chiral center, leading to two enantiomers. The study of these enantiomers is crucial, as their different interactions in biological systems can lead to varying therapeutic effects.
  • Biomedical Research: It has been investigated for potential applications in the treatment of certain conditions, including attention deficit hyperactivity disorder (ADHD) and depression, showcasing its importance in pharmaceutical chemistry.
  • Amine Functional Group: The presence of an amino group in its structure leads to interesting reactivity patterns, facilitating various chemical reactions like alkylation and amidation, which are essential in organic synthesis.

Applications in Industry

The versatility of 2-amino-2-methyl-1-phenyl-propan-1-ol extends beyond pharmaceutical development:

  • As a Precursor: It can be utilized as a precursor in the synthesis of other valuable compounds, amplifying its significance in chemical manufacturing.
  • Research Tool: Chemists often use this compound as a model system to investigate the behavior and interaction of amines in various chemical environments.

Conclusion

With its multifaceted nature, 2-amino-2-methyl-1-phenyl-propan-1-ol represents a compelling subject of study in the realm of chemistry. As one scientist aptly put it, “The deeper you delve into the intricacies of compounds like this, the more you uncover the elegance and complexity of chemical interactions.”

Synonyms
2-amino-2-methyl-1-phenylpropan-1-ol
DTXSID701274455
alpha-(1-amino-1-methylethyl)benzenemethanol
DTXCID201447461
868-408-9
34405-42-0
2-Phenyl-1,1-dimethylethanolamine
2-Amino-2-methyl-1-phenyl-1-propanol
2-AMINO-2-METHYL-1-PHENYL-PROPAN-1-OL
MFCD01697285
b-Hydroxyl Phentermine
USAF CS-8
NSC 17705
BRN 2802507
1-Propanol, 2-amino-2-methyl-1-phenyl-
Benzenemethanol, alpha-(1-amino-1-methylethyl)-
NSC17705
Benzenemethanol, a-(1-amino-1-methylethyl)-
3-13-00-01799 (Beilstein Handbook Reference)
SCHEMBL411887
Benzenemethanol, .alpha.-(1-amino-1-methylethyl)-
1phenyl-2-methyl-2-amino-propanol
JBA40542
NSC-17705
AKOS006279578
AT30646
SB76713
SY223203
DS-010162
CS-0247814
I+/--(1-Amino-1-methylethyl)benzenemethanol
EN300-374045
Z1198157843