Skip to main content

N-Phenylglycine amide

ADVERTISEMENT
Identification
Molecular formula
C8H10N2O
CAS number
7096-66-6
IUPAC name
2-amino-2-phenyl-acetamide
State
State

At room temperature, 2-Amino-2-phenylacetamide is in a solid state. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
354.20
Boiling point (Kelvin)
627.35
General information
Molecular weight
150.18g/mol
Molar mass
150.1790g/mol
Density
1.2220g/cm3
Appearence

2-Amino-2-phenylacetamide typically appears as a crystalline solid. It is generally white or off-white in color. The solid state of the compound is usually powdery or may form small crystals.

Comment on solubility

Solubility of 2-amino-2-phenyl-acetamide

2-amino-2-phenyl-acetamide, often referred to as phenylalanine amide, exhibits unique solubility characteristics that are particularly noteworthy:

  • Water Solubility: This compound is generally considered to be moderately soluble in water, which can be attributed to the presence of the amino group (-NH2) that promotes hydrogen bonding with water molecules.
  • Organic Solvents: It demonstrates greater solubility in polar organic solvents such as ethanol and methanol, revealing its ability to interact with these solvents effectively.
  • Temperature Dependence: The solubility of 2-amino-2-phenyl-acetamide can increase with temperature, which is a common trait among many organic compounds.

It’s essential to note that while its solubility in water is significant, excessive amounts may lead to issues such as precipitation, influencing its practical applications in various industries. As with many amides, the overall solubility behavior can be complex, often requiring careful consideration of specific conditions and solvent systems. “Understanding solubility is crucial for optimizing the use of compounds in formulations and synthesis.”

Interesting facts

Exploring 2-Amino-2-phenyl-acetamide

2-Amino-2-phenyl-acetamide is a fascinating compound that has garnered attention due to its unique properties and potential applications in various fields. Here are some interesting facts about this compound:

  • Structural Significance: This compound features an amino group and an acetamide group attached to a phenyl ring, highlighting its potential for various reactivity pathways in organic synthesis.
  • Pharmaceutical Relevance: 2-amino-2-phenyl-acetamide is often investigated for its biological activities. It has a potential role in drug design, particularly in targeting specific receptors or enzymes.
  • Dynamic Interactions: The presence of the amino group allows for hydrogen bonding interactions, which can significantly influence the compound's solubility and biological activity, making it a subject of interest in medicinal chemistry.
  • Versatile Precursor: This compound can serve as a precursor in the synthesis of various pharmaceuticals and agrochemicals, showcasing its versatility in chemical manufacturing.

As a compound with a rich array of functionalities, 2-amino-2-phenyl-acetamide invites further exploration and study. Its intricate structure and the potential implications in the field of medicine exemplify the beauty of chemistry as it continues to play a crucial role in advancements in health and technology.

In the words of a noted chemist, "The details of molecular interactions are what guide the creation of new therapies and innovations."

Synonyms
2-Amino-2-phenylacetamide
ACETAMIDE, 2-AMINO-2-PHENYL-
EINECS 211-849-3
NSC 47695
BRN 0972472
1-14-00-00592 (Beilstein Handbook Reference)
211-849-3
kiyrsyyovdhspg-uhfffaoysa-n
700-63-0
2-Amino-2-phenyl-acetamide
DL-2-PHENYLGLYCINAMIDE
Benzeneacetamide, .alpha.-amino-
NSC47695
H-Phg-NH HCl
Benzeneacetamide, alpha-amino-
MFCD06799064
MFCD00025498
WLN: ZYR&VZ
alpha-Amino-benzeneacetamide
SCHEMBL544671
DTXSID20863871
AAA70063
AC-684
NSC-47695
STK097875
AKOS000204934
AKOS016038186
AKOS037748796
s10736
AS-58496
SY009237
SY017679
DB-005912
DB-013454
NS00079555
P2402
2-Phenyl-2-aminoacetamide;Aminophenylacetamide
EN300-25412
Z57204607