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Tryptophanol

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Identification
Molecular formula
C11H14N2O
CAS number
526-55-6
IUPAC name
2-amino-3-(1H-indol-3-yl)propan-1-ol
State
State

Tryptophanol is a solid at room temperature.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
370.30
Boiling point (Kelvin)
643.45
General information
Molecular weight
190.24g/mol
Molar mass
190.2410g/mol
Density
1.2850g/cm3
Appearence

Tryptophanol is typically a white to off-white crystalline solid. It may appear as a fine powder or in a crystalline form, depending on the method of preparation and handling.

Comment on solubility

Solubility of 2-amino-3-(1H-indol-3-yl)propan-1-ol

The solubility of 2-amino-3-(1H-indol-3-yl)propan-1-ol in various solvents presents intriguing characteristics that are often influenced by its molecular structure. This compound contains both hydrophilic and hydrophobic regions due to the presence of the indole moiety and the amino and alcohol functional groups. As a result, its solubility can be summarized as follows:

  • Water: This compound is expected to have moderate to high solubility in water, attributable to the amino and alcohol groups which can form hydrogen bonds with water molecules.
  • Organic Solvents: It may show varying solubility in organic solvents due to the indole structure, which can interact favorably with non-polar solvents, potentially leading to increased solubility in solvents like ethanol and dimethyl sulfoxide (DMSO).
  • Weaker Solvents: In solvents with low polarity, solubility might decrease, illustrating the importance of the solvent's nature.

To sum up, the solubility of 2-amino-3-(1H-indol-3-yl)propan-1-ol can be described as solvent-dependent. This underscores the importance of considering the solvent environment for practical applications and further studies.

Interesting facts

Interesting Facts about 2-Amino-3-(1H-Indol-3-yl)propan-1-ol

2-Amino-3-(1H-indol-3-yl)propan-1-ol, often referred to as a derivative of the amino acid tryptophan, has intrigued scientists due to its structural similarity to neurotransmitters. Here are some captivating aspects of this compound:

  • Biological Significance: This compound showcases a connection to essential biological processes, particularly in neurotransmission, where its indole structure may interact with various receptors in the brain.
  • Medicinal Chemistry: Research has indicated that compounds related to this structure may have potential in drug development, particularly in treating mood disorders. As the saying goes, "Chemistry is the path to well-being."
  • Natural Occurrence: The indole moiety is a crucial building block in many natural products, and understanding this compound can provide insights into many biologically relevant pathways.
  • Research Potential: The study of this compound can contribute to the growing field of neuropharmacology, where the focus is on the impact of compounds on neurological functions.
  • Structural Analysis: Understanding the 3D conformation of this molecule is vital, as it influences its biological activity and interaction with various targets in the body.

In summary, 2-amino-3-(1H-indol-3-yl)propan-1-ol stands as a promising candidate in the world of medicinal chemistry and neurobiology, making it a fascinating subject of study.

Synonyms
526-53-4
EINECS 208-392-7
1H-INDOLE-3-PROPANOL, beta-AMINO-
2-amino-3-(1H-indol-3-yl)propan-1-ol
beta-Amino-1H-indole-3-propanol
MFCD00037970
SCHEMBL143812
DTXSID00967028
UDQCRUSSQAXPJY-UHFFFAOYSA-N
AAA52653
STR07037
MFCD00069710
2-Amino-3-(3-indolyl)-1-propanol
AKOS006228060
SY005423
NS00043423
EN300-69567
E78552
(2S)-2-Amino-3-(1H-indole-3-yl)-1-propanol
Z1069312128