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Hypoglycin A

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Identification
Molecular formula
C7H11NO2
CAS number
156-10-5
IUPAC name
2-amino-3-(2-methylenecyclopropyl)propanoic acid
State
State

At room temperature, Hypoglycin A is typically a solid.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
129.17g/mol
Molar mass
129.1510g/mol
Density
1.2850g/cm3
Appearence

Hypoglycin A is a white crystalline compound when isolated in its pure form. It is typically provided as a crystalline powder for research and experimental purposes.

Comment on solubility

Solubility of 2-amino-3-(2-methylenecyclopropyl)propanoic acid

The solubility of 2-amino-3-(2-methylenecyclopropyl)propanoic acid is influenced by several factors that are important to consider:

  • Polarity: The presence of both amino and carboxylic acid functional groups indicates that the compound is polar. This polar character generally favors solubility in polar solvents such as water.
  • Hydrogen Bonding: The amino group (-NH2) and carboxylic acid group (-COOH) can participate in hydrogen bonding, which can enhance its solubility in water.
  • Hydrophobic region: The methylenecyclopropyl group may introduce hydrophobic characteristics, potentially reducing solubility in aqueous environments. This suggests that solubility may be moderate rather than high.
  • pH Influence: The solubility may vary with pH, as ionization of the carboxylic acid group can occur in alkaline conditions, usually increasing solubility.

In summary, while it is likely that 2-amino-3-(2-methylenecyclopropyl)propanoic acid is soluble in polar solvents due to its functional groups, the competing hydrophobic characteristics of the cyclopropyl component may lead to variable solubility. Testing in specific solvents is recommended for precise quantification.

Interesting facts

Interesting Facts about 2-amino-3-(2-methylenecyclopropyl)propanoic acid

2-amino-3-(2-methylenecyclopropyl)propanoic acid, often abbreviated as AMPA, is a fascinating compound that belongs to the class of amino acids. Its unique structural features lend it interesting properties and potential applications. Here are some noteworthy aspects:

  • Structural Diversity: This compound features a side chain that includes a methylenecyclopropyl group, which is relatively rare among amino acids. This structural diversity can lead to novel interactions in biological systems.
  • Biological Relevance: Amino acids are the building blocks of proteins, playing a crucial role in various biological processes. The presence of an amino group and a carboxylic acid group in AMPA makes it a key ingredient in protein synthesis.
  • Potential Applications: Due to its unique side chain, AMPA may have potential applications in pharmaceuticals, particularly in the development of new drugs targeting various biochemical pathways.
  • Stereochemistry: The molecule exhibits chirality, which can significantly influence its interaction with biological targets. This emphasizes the importance of stereochemistry in drug design and effectiveness.
  • Research Interest: Scientists are increasingly drawn to investigate the properties and implications of AMPA within the field of medicinal chemistry, particularly its role in modulating specific receptor activities.

As we delve deeper into the world of amino acids, compounds like 2-amino-3-(2-methylenecyclopropyl)propanoic acid remind us that even the smallest structural differences can lead to significant variations in function and application, highlighting the intricate relationship between structure and activity in biochemical systems.

Synonyms
Hypoglycine
Hypoglycine A
Hypoglycin A
2-Methylenecyclopropanylalanine
2-amino-3-(2-methylenecyclopropyl)propanoic acid
(S)-Hypoglycine A, 85%
.beta.-(Methylenecyclopropyl)alanine
.alpha.-Aminomethylenecyclopropanepropionic acid
.alpha.-Amino-2-methylenecyclopropanepropionic acid
Cyclopropanepropanoic acid, .alpha.-amino-2-methylene-
L-.alpha.-Amino-.beta.-methylenecyclopropanepropionic acid
.alpha.-Amino-.beta.-(2-methylenecyclopropyl)propionic acid
L-Hypoglycin A
Cyclopropanealanine, L-
SCHEMBL956162
2-MethyleneL-Cyclopropanealanine
WLN: L3YTJ AU1 B1YZVQ
DTXSID50871621
CHEBI:136270
OOJZCXFXPZGUBJ-UHFFFAOYSA-N
3-(2-Methylenecyclopropyl)alanine
3-(2-Methylidenecyclopropyl)alanine
Cyclopropanepropionic acid, L-(+)-
3-(2-Methylenecyclopropyl)alanine #
NSC303803
AKOS006277118
NS00015432
2-amino-3-(2-methylenecyclopropyl)propionic acid