Interesting facts
Interesting Facts about 2-amino-3-(3-fluorophenyl)propanoic acid
2-amino-3-(3-fluorophenyl)propanoic acid, often abbreviated as 3-F-APA, is a fascinating compound that showcases the intersection of medicinal chemistry and neuropharmacology. Here are some key points about this intriguing molecule:
- Structural Significance: This compound features an amino acid backbone—critical for many biological processes. Its unique structure includes a fluorophenyl group, which plays an essential role in modulating its biological activity.
- Biological Activity: Compounds similar to 2-amino-3-(3-fluorophenyl)propanoic acid are often investigated for their potential as neuroprotective agents. They may influence neurotransmitter systems, particularly in the context of excitatory amino acids that are implicated in various neurological disorders.
- Fluorine's Role: The presence of fluorine in the phenyl group can enhance the compound's lipophilicity, potentially increasing its ability to cross the blood-brain barrier, a significant factor in drug development. Fluorine is also known to influence the metabolic stability of pharmaceuticals.
- Research and Applications: Researchers are continuously exploring the therapeutic potential of this compound. It has garnered attention for its possible applications in treating conditions such as depression and anxiety by modulating synaptic transmission.
- Analytical Techniques: The study of 2-amino-3-(3-fluorophenyl)propanoic acid often involves various analytical techniques (such as NMR and mass spectrometry) to determine its purity and biological activity, showcasing the importance of precision in chemical analysis.
In summary, 2-amino-3-(3-fluorophenyl)propanoic acid is a compound rich with potential, serving as a prime example of how modifications at the molecular level can lead to significant changes in activity and application. The study of such compounds not only broadens our understanding of chemistry but could also pave the way for new therapeutic agents.
Synonyms
3-Fluoro-dl-phenylalanine
456-88-2
2629-54-1
H-DL-PHE(3-F)-OH
3-Fluorophenylalanine
3-Fluoro-D-phenylalanine
2-amino-3-(3-fluorophenyl)propanoic acid
m-Fluorophenylalanine
m-Fluoro-dl-phenylalanine
DL-3-Fluorophenylalanine
DL-Phenylalanine, 3-fluoro-
Alanine, (3-fluorophenyl)-
DL-3-(3-Fluorophenyl)alanine
Phenylalanine, 3-fluoro-
Alanine, 3-(m-fluorophenyl)-, DL-
MFCD00004273
ALANINE, 3-(m-FLUOROPHENYL)-
NSC 208960
EINECS 220-104-1
NSC 41871
2-Amino-3-(3-fluoro-phenyl)-propionic acid
MFCD00066449
m-Fluorophenylalanine (VAN)
EINECS 207-272-1
MFCD00066450
2-Amino-3-(3-fluorophenyl)propionic Acid
WLN: QVYZ1R CF
SCHEMBL42948
CHEMBL50636
FLUORO-DL-PHENYLALANINE
(3-FLUOROPHENYL)ALANINE
NSC41871
DL-Phenylalanine, 3-fluoro-(9CI)
BBL100144
NSC-41871
NSC208960
STL511732
AKOS000168457
AKOS016843009
AB00349
AB02698
AB02699
AC-9898
CS-W017055
HY-W016339
NSC-208960
PS-6600
SY035269
SY035324
SY046381
DB-040898
DB-045018
DB-046919
DB-070672
F0169
EN300-142283
F2147-6669
220-104-1
Solubility of 2-amino-3-(3-fluorophenyl)propanoic acid
The solubility of 2-amino-3-(3-fluorophenyl)propanoic acid, also known as an amino acid derivative, can be influenced by several factors. Generally, this compound demonstrates varying degrees of solubility in different solvents.
Key Points on Solubility:
In summary, while 2-amino-3-(3-fluorophenyl)propanoic acid shows promising solubility characteristics, the extent can diverge based on the solvent used and environmental conditions. As a rule of thumb, “like dissolves like”, and understanding these principles is crucial when predicting solvent interactions.