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Levodopa

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Identification
Molecular formula
C9H11NO4
CAS number
59-92-7
IUPAC name
2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid
State
State

At room temperature, levodopa is in a solid state, typically existing as a powder. When stored under normal conditions, it remains stable as a solid without undergoing sublimation or other state changes.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.15
Boiling point (Celsius)
-273.15
Boiling point (Kelvin)
0.00
General information
Molecular weight
197.19g/mol
Molar mass
197.1880g/mol
Density
1.5099g/cm3
Appearence

Levodopa appears as a white or slightly off-white crystalline powder. It is often found in a solid state and can have a slightly glossy texture. Due to its chemical nature, it may display some light reflections but is generally opaque.

Comment on solubility

Solubility of 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid

2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid, with the chemical formula C9H11NO4, exhibits unique solubility characteristics that can be particularly interesting for chemists.

Key Points on Solubility

  • Polar Characteristics: The presence of hydroxyl groups (-OH) in its structure suggests that this compound is likely to be polar, enhancing its solubility in polar solvents such as water.
  • Hydrophilic Interactions: The amino group (-NH2) can form hydrogen bonds with water molecules, further contributing to its solubility.
  • Solubility in Organic Solvents: While it is soluble in water, the compound may have limited solubility in non-polar organic solvents due to its polar functional groups.

When addressing solubility, it's important to consider that factors such as temperature and pH can significantly influence the solubility behavior. For example, the solubility of this compound might increase at higher temperatures as kinetic energy promotes dissolution.

In summary, 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid is expected to be soluble in water due to its polar functional groups and ability to engage in hydrogen bonding. However, its solubility in organic solvents may be limited, illustrating the intricate balance between molecular structure and solubility behavior.

Interesting facts

Interesting Facts about 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid

This fascinating compound is commonly known as Tyrosine, which is an important amino acid that plays a pivotal role in various biological processes. Here are some interesting facts about it:

  • Biological Significance: It is a non-essential amino acid, meaning that our bodies can synthesize it from phenylalanine, another amino acid.
  • Precursor Role: Tyrosine serves as a precursor for the synthesis of important neurotransmitters such as dopamine, norepinephrine, and epinephrine.
  • Dietary Sources: Foods rich in protein, like chicken, turkey, fish, dairy products, and nuts, serve as excellent sources of tyrosine in our diet.
  • Health Benefits: Supplementing tyrosine has been studied for its potential to improve cognitive performance under stressful conditions and enhance mood.
  • Structural Characteristics: The compound's structure includes a phenolic ring, which is characteristic of many biologically active molecules, affecting its reactivity and interaction with other cellular components.

Moreover, its unique chemical properties facilitate a variety of applications in both health and science. As scientists continue exploring the benefits of this amino acid, the implications for neurology and nutrition become increasingly clear.

In summary, 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid stands not just as a building block of proteins, but also as a significant player in the intricate biochemical networks of life.

Synonyms
55-40-3
3-Hydroxy-alpha-methyl-DL-tyrosine
DL-Methyldopa
555-29-3
3-Hydroxy-alpha-methyltyrosine
Mulfasin
Metholes
2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
(+/-)-methyldopa
rac Alpha-Methyl DOPA
EINECS 209-088-7
.alpha.-Methyl dopa
Methyldopa (Racemic)
Methyldopa anhydrous, (+/-)-
L-(.alpha.-Md)
Dl-.alpha.-methyl dopa
.alpha.-Methyldopa, L-
EINECS 200-232-4
Racemic .alpha.-methyldopa
Aldomin
(+/-)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine
L-Methyldopa
33TD13T99R
L-.alpha.-Methyldopa
.alpha.-Methyl-L-dopa
.alpha.-Methyl-L-(3,4-dihydroxyphenyl)alanine
L-.alpha.-Methyl-(3,4-dihydroxyphenyl)alanine
Aldomine
(S)-(-)-.alpha.-Methyldopa
.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)-L-alanine
a-methyl-l-dopa
Nr.C 2294
DL-alpha-Methyl DOPA
L-(-)-.alpha.-Methyl-.beta.-(3,4-dihydroxyphenyl)alanine
NCI-C55721
racemic alpha-Methyldopa
(+-)-alpha-Methyldopa
MK 351
L-Tyrosine, 3-hydroxy-.alpha.-methyl-
2-Methyl-3-(3,4-dihydroxyphenyl)alanine
Mk. b51
Tyrosine, 3-hydroxy-alpha-methyl-
SR-01000075631
Elanpres
Equibar
LMethyldopa
alphaMethylLdopa
LalphaMethyldopa
UNII-33TD13T99R
Methyl-dopa
3-Hydroxy-.alpha.-methyl-L-tyrosine
Tyrosine, 3-hydroxy-.alpha.-methyl-
()Methyldopa
.alpha.-Medopa
3,4-Dihydroxy-2-methylphenylalanine #
L(alphaMd)
Methyldopa dl-form
.alpha.-Methyldopa
L-a-Methyl-DOPA
.alpha.-Methyl-L-3,4-dihydroxyphenylalanine
D-?-Methyl DOPA
DL-Tyrosine, 3-hydroxy-alpha-methyl-
rac ?-Methyl DOPA
DL-alpha-Methyl-DOPA
? METHYLDOPA
rac alpha -Methyl DOPA
Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-
CHEMBL718
2-Methyl-3-(3,4-dihydroxyphenyl)-DL-alanine
3HydroxyalphamethylLtyrosine
Lopac0_000770
SCHEMBL196981
WLN: QVXZ1&1R CQ DQ
METHYLDOPA DL-FORM [MI]
ALANINE, 3-(3,4-DIHYDROXYPHENYL)-2-METHYL-, DL-
DTXSID50859484
DTXSID60970356
CHEBI:180994
HMS3259C21
HMS3262I22
HMS3266O08
AAA55530
ALBB-024010
BCP28393
CAA79915
Tox21_500770
(+/-)-.ALPHA.-METHYLDOPA
alphaMethylL3,4dihydroxyphenylalanine
LalphaMethyl3,4dihydroxyphenylalanine
3(3,4Dihydroxyphenyl)2methylLalanine
AKOS003273681
AKOS017258656
AC-8433
CCG-204855
LP00770
NC00520
SDCCGSBI-0050748.P005
L()3(3,4Dihydroxyphenyl)2methylalanine
NCGC00015631-03
NCGC00015631-04
NCGC00015631-05
NCGC00015631-09
NCGC00094109-01
NCGC00094109-02
NCGC00261455-01
AC-11788
SBI-0050748.P004
3-Hydroxy-alpha-methyltyrosine sesquihydrate
Alanine,4-dihydroxyphenyl)-2-methyl-, L-
alpha-methyl-3,4-dihydroxy-dl-phenylalanine
alphaMethylbeta(3,4dihydroxyphenyl)Lalanine
DB-018032
DB-052752
EU-0100770
NS00079124
L()alphaMethylbeta(3,4dihydroxyphenyl)alanine
L()beta(3,4Dihydroxyphenyl)alphamethylalanine
2-(3,4-dihydroxybenzyl)-2-aminopropanoic acid
3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine
EN300-297472
H34296
M 7277
Alanine,4-dihydroxyphenyl)-2-methyl-, L-(-)-
alpha-Methyl-DL-beta-3,4-Dihydroxyphenylalanine
L001029
L2Amino2methyl3(3,4dihydroxyphenyl)propionic acid
L2Amino3(3,4dihydroxyphenyl)2methylpropionic acid
SR-01000076007
(?)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine
(y)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine
DL-2-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE
SR-01000075631-1
SR-01000075631-3
SR-01000076007-1
Q27256299
2-amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid
2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoicacid
DL-.ALPHA.-METHYL-3-(3,4-DIHYDROXYPHENYL)ALANINE
L(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine
L-(-)-.beta.-(3,4-Dihydroxyphenyl)-.alpha.-methylalanine
( inverted question mark)-3-(3,4-dihydroxyphenyl)-2-methyl-DL-alanine
2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-2- METHYL-PROPIONIC ACID(CATECHOL METABOLITE)