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L-Tyrosine

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Identification
Molecular formula
C9H11NO3
CAS number
60-18-4
IUPAC name
2-amino-3-(4-hydroxyphenyl)propanoic acid
State
State

At room temperature, L-Tyrosine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
343.00
Melting point (Kelvin)
616.15
Boiling point (Celsius)
313.60
Boiling point (Kelvin)
586.75
General information
Molecular weight
181.19g/mol
Molar mass
181.1910g/mol
Density
1.4609g/cm3
Appearence

L-Tyrosine appears as white to off-white crystals or crystalline powder. It is typically odorless.

Comment on solubility

Solubility of 2-amino-3-(4-hydroxyphenyl)propanoic acid

The solubility of 2-amino-3-(4-hydroxyphenyl)propanoic acid (C9H11NO3), also known as L-DOPA, is a fascinating subject due to its unique structural features.

General Solubility Characteristics

This compound exhibits differing solubility in various solvents:

  • Water: L-DOPA is soluble in water, primarily due to its polar amino and carboxylic acid functional groups. This allows for effective hydrogen bonding with water molecules.
  • Alcohols: It demonstrates moderate solubility in alcohols, which can also engage in hydrogen bonding, though less effectively than water.
  • Non-polar Solvents: Conversely, L-DOPA is poorly soluble in non-polar solvents due to its hydrophilic nature.

Factors Influencing Solubility

Several factors contribute to its solubility profile:

  • pH Levels: The solubility can change significantly with pH, particularly around its pKa values, which can lead to the formation of charged species that are more soluble.
  • Temperature: Higher temperatures generally increase solubility in many solvents, making temperature an important variable for any experimental setup.
  • Concentration: Concentration effects can lead to saturation, where the maximum solubility is reached, impacting further dissolution.

In conclusion, understanding the solubility of 2-amino-3-(4-hydroxyphenyl)propanoic acid is crucial for its application in fields such as pharmacology and medicinal chemistry. Its significant solubility in water and variability with pH exemplify the importance of these factors in determining effective uses of chemical compounds.

Interesting facts

Interesting Facts about 2-Amino-3-(4-hydroxyphenyl)propanoic Acid

2-amino-3-(4-hydroxyphenyl)propanoic acid, often referred to as a derivative of the more commonly known amino acids, holds a special place in biochemistry and pharmaceuticals. Here are some captivating aspects of this compound:

  • Amino Acid Structure: This compound can be categorized as a non-proteinogenic amino acid, meaning it is not incorporated into proteins during translation. However, its structure resembles that of essential amino acids, providing insights into biochemical pathways.
  • Biological Significance: The presence of the amino and hydroxyl groups in its structure suggests potential biological activity, including roles in neurotransmission or as a metabolic intermediate.
  • Research Potential: Due to its hydroxyphenyl group, this compound may be studied for its antioxidant properties. Compounds with similar structures are often investigated for their ability to scavenge free radicals.
  • Pharmaceutical Applications: Molecules that bear such structural characteristics are frequently evaluated for pharmacological properties, including anti-inflammatory, analgesic, or neuroprotective effects.
  • Chemoenzymatic Synthesis: Its synthesis may be achieved through chemoenzymatic pathways, providing insights into both organic synthesis and enzymology, bridging the gap between chemistry and biological systems.

In summary, 2-amino-3-(4-hydroxyphenyl)propanoic acid serves not only as a fascinating subject for study in the field of chemistry but also opens avenues for exploration in biochemistry and pharmacology. Its structural nuances and potential applications underline the interconnectedness of different scientific disciplines.

Synonyms
DL-Tyrosine
556-03-6
H-DL-Tyr-OH
2-amino-3-(4-hydroxyphenyl)propanoic acid
Tyrosine, DL-
tyrosin
(.+-.)-Tyrosine
MFCD00063074
A9BAT9B32M
NSC 205006
EINECS 209-113-1
NSC-205006
DL-TYROSINE-BETA-13C
AI3-18479
DL-4-Hydroxyphenylalanine-15N
L-Tryosine
CHEBI:18186
DTXSID50859040
NSC205006
L-TYROSINE-BETA-13C
Benzenepropanoic acid, (S)-
25619-78-7
(+-)-Tyrosine
2-amino-3-(4-hydroxyphenyl)-propanoic acid
TYROSINE, (L)
3-(4-Hydroxyphenyl)-DL-alanine
UNII-A9BAT9B32M
NSC9973
L-TYROSINE, [1-14C]-
dl-p-tyrosine
DL-Tyrozine
Tyrosine #
(2s)-tyrosine
(DL)-Tyrosine
DL-Tyrosine 25GR
DL-Tyrosine, 99%
(.+/-.)-Tyrosine
.alpha.-Amino-.beta.-(4-hydroxyphenyl)propionic acid
SCHEMBL1580
NCIOpen2_001002
(+/-)-TYROSINE
L-Tyrosine, non animal origin
CHEMBL108615
DTXCID00199786
Pharmakon1600-01300046
BCP28669
HY-Y0123
NSC-9973
NSC82624
AC2634
BBL007890
NSC760112
STK387122
AKOS000119676
AKOS016050613
AB00245
AB02505
CCG-202972
FT32753
NSC-760112
UPCMLD0ENAT5883816:001
AC-24050
AS-11716
SY013607
SY014304
2-azaniumyl-3-(4-hydroxyphenyl)propanoate
2-amino-3-(4-hydroxyphenyl)propionic acid
DB-052763
DL-Tyrosine, puriss., >=99.0% (NT)
2-amino-3-(4-hydroxyphenyl)-propionic acid
CS-0008411
EU-0066703
NS00080506
T0549
EN300-17972
C01536
SR-01000597209
(+/-)-2-Amino-3-(4-hydroxyphenyl)propionic acid
SR-01000597209-1
BRD-A20781140-001-01-7
Q27102882
Q27115119
Z57127380
F0345-2313
5C49731F-8609-4ECA-909D-8E4C8515147E
(R)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-D-alanine
209-113-1