Skip to main content

Indoloquinone

ADVERTISEMENT
Identification
Molecular formula
C17H20Cl2N2O2
CAS number
68173-32-8
IUPAC name
2-amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic acid
State
State

At room temperature, Indoloquinone exists as a solid substance. It generally maintains its solid state under standard laboratory conditions.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
425.00
Boiling point (Kelvin)
698.15
General information
Molecular weight
352.26g/mol
Molar mass
352.2410g/mol
Density
1.4504g/cm3
Appearence

Indoloquinone typically presents as a crystalline solid. It can occur in powder form and its color may vary based on its purity and specific composition.

Comment on solubility

Solubility of 2-amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic acid

The solubility of 2-amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic acid can be quite intriguing due to its complex structure. Here are some important points to consider:

  • Polar Nature: The presence of the amino group and the acid functional group contributes to its polar characteristics, suggesting that it may be more soluble in polar solvents.
  • Hydrophilicity: The compound's structure includes elements that enhance its hydrophilicity, promoting solubility in water-based environments.
  • Saturation: Its solubility can also be influenced by factors such as temperature and concentration, which affect the saturation point.
  • pH Levels: Solution pH can significantly impact the solubility of this compound—higher acidity may facilitate dissolution due to protonation of the amino group.

In summary, one can expect this compound to demonstrate varying solubility, which can be optimized by manipulating environmental conditions. As the saying goes, "solubility is key to bioavailability," making it essential to consider these factors in practical applications.

Interesting facts

Interesting Facts about 2-Amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic Acid

This compound, often referred to as a derivative of indole, belongs to a fascinating class of organic compounds known for their biological activity. It presents intriguing features that make it significant in the field of medicinal chemistry:

  • Structure & Function: The structure of this compound includes an amino acid (propanoic acid) backbone attached to an indole moiety, which is well-known for its occurrence in many natural compounds and pharmaceuticals.
  • Potential Therapeutic Applications: With its bis(2-chloroethyl)amino group, this compound is structurally related to nitrogen mustards, a class of chemotherapeutic agents. Such compounds have been studied for their ability to interact with DNA and exhibit anti-cancer properties.
  • Research Insights: Studies have shown that indole derivatives can also exhibit anti-inflammatory and anti-microbial properties, opening up avenues for research into how this compound might impact these fields.
  • Drug Development: The formation of compounds like this one is a vital step in drug design, where understanding structure-activity relationships can lead to the development of more effective therapies.

As a chemistry student or enthusiast, you might find it fascinating that the study of such compounds leads to a greater understanding of how chemical modifications can drastically alter biological activity. As noted by chemists, "The beauty of chemistry lies in its ability to connect seemingly disparate elements into revolutionary solutions for health and wellness."

In summary, 2-amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic acid exemplifies the interplay between structure and function in medicinal chemistry, making it a compound of considerable interest for ongoing research and therapeutic development.

Synonyms
TRYPTOPHAN MUSTARD
MP 955
DL-Tryptophan mustard
Tryptophan mustard, DL-
153-88-8
5-(Bis(2-chloroethyl)amino)-DL-tryptophan
UNII-IV1K341O5Z
NSC 62403
BRN 3997356
IV1K341O5Z
NSC-62403
Tryptophan, 5-(bis(2-chloroethyl)amino)-, DL-
2-amino-3-[5-[bis(2-chloroethyl)amino]-1H-indol-3-yl]propanoic acid
5-Bis(2-chloroethyl)amino-DL-tryptophan
TRYPTOPHAN, 5-(BIS(2-CHLOROETHYL)AMINO)-
5-[Bis(2-chloroethyl)amino]-DL-tryptophan
TRYPTOPHANE MUSTARD
NCIOpen2_008286
NSC62403
WLN: T56 BMJ D1YZVQ GN2G2G
DL-Tryptophan, 5-[bis(2-chloroethyl)amino]-
Q27280908