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Methionine

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Identification
Molecular formula
C5H11NO2S
CAS number
63-68-3
IUPAC name
2-amino-3-methyl-3-sulfanyl-butanoic acid
State
State

At room temperature, methionine is found in a solid state. It is stable and non-volatile, making it easy to handle in a variety of chemical processes and applications.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
149.21g/mol
Molar mass
149.2110g/mol
Density
1.3400g/cm3
Appearence

Methionine appears as a white crystalline powder. It has a slight sulfide odor due to the presence of a thioether group in its structure. Its appearance might vary slightly when hydrated or mixed with other substances.

Comment on solubility

Solubility of 2-amino-3-methyl-3-sulfanyl-butanoic acid (C5H11NO2S)

2-amino-3-methyl-3-sulfanyl-butanoic acid, often referred to as a thiol-containing amino acid, demonstrates interesting solubility characteristics due to its unique molecular structure. It is essential to consider several factors that impact the solubility of this compound:

  • Polarity: The presence of both amino (-NH2) and carboxylic acid (-COOH) groups contributes to the polarity of the molecule, enhancing its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the amino acid to form hydrogen bonds with water molecules significantly increases its solubility. The -NH2 and -COOH groups can engage in strong interactions with water.
  • Thiol Group Impact: The sulfanyl (-SH) group does add a degree of hydrophobic character compared to non-thiol amino acids, but its influence on overall solubility is somewhat mitigated by the other polar functional groups.

In dissolution processes, the interplay between these functional groups means that:

  1. The compound is expected to be highly soluble in aqueous solutions.
  2. It may have lower solubility in non-polar organic solvents due to its hydrophilic nature.

In summary, while 2-amino-3-methyl-3-sulfanyl-butanoic acid is primarily soluble in water due to its polar characteristics and ability to form hydrogen bonds, the presence of the thiol group adds a layer of complexity to its solubility profile in different environments or solvents.

Interesting facts

Interesting Facts about 2-amino-3-methyl-3-sulfanyl-butanoic acid

2-amino-3-methyl-3-sulfanyl-butanoic acid, commonly known as L-Cysteine, is a fascinating compound in the field of biochemistry and nutrition. Here are some intriguing aspects of this amino acid:

  • Essential Building Block: L-Cysteine plays a crucial role in protein synthesis. It is one of the twenty standard amino acids and is classified as a non-essential amino acid, meaning that the body can synthesize it from other compounds.
  • Rich in Sulfur: This compound contains a thiol (-SH) group, which is responsible for its unique properties. The sulfur atom can form disulfide bonds, which are critical in stabilizing protein structures, especially in enzymes and structural proteins.
  • Antioxidant Properties: L-Cysteine is a precursor to the antioxidant glutathione, contributing to the body's defense against oxidative stress. Glutathione is vital for detoxification processes and plays a role in immune function.
  • Health Benefits: It has been studied for various health benefits, including supporting liver detoxification, promoting skin health, and enhancing muscle recovery after exercise.
  • Food Sources: You can find L-Cysteine in high-protein foods such as chicken, turkey, yogurt, cheese, and legumes, making it an integral part of a balanced diet.

As a notable member of the amino acid family, L-Cysteine’s diverse roles and properties make it a subject of research in both biological and health sciences. It serves as an excellent reminder of the complexity and importance of life’s molecular building blocks!

Synonyms
DL-Penicillamine
52-66-4
2-Amino-3-mercapto-3-methylbutanoic acid
3,3-Dimethyl-DL-cysteine
DL-3-Mercaptovaline
(+-)-Penicillamine
3-Sulfanylvaline
DL-beta-Mercaptovaline
D,L-Penicillamine
2-amino-3-methyl-3-sulfanylbutanoic acid
3-Mercaptovaline
beta-Mercaptovaline
2-Amino-3-mercapto-3-methylbutyric acid
Valine, 3-mercapto-
MFCD00004856
DL-Valine, 3-mercapto-
(+/-)-penicillamine
DL-.beta.-Mercaptovaline
NSC241261
Penicillamine, (+/-)-
2XOP7Y1H98
CHEBI:50868
NSC-22880
NSC-44656
3,3-dimethylcysteine
Dimethylcysteine
D-Penicilamine
l-3-Mercaptovaline
Cysteine, 3,3-dimethyl-
.beta.,.beta.-Dimethylcysteine
Penicillamina [DCIT]
dl-beta,beta-Dimethylcysteine
771431-20-0
Valine, 3-mercapto-, DL-
valine, 3-mercapto
3,3-Dimethyl-L-cysteine
H-beta,beta-Dimethyl-Cys-OH;H-beta-Mercapto-Val-OH
EINECS 200-147-2
NSC 22880
NSC 44656
BRN 2039817
UNII-2XOP7Y1H98
Penicilllamine
D-Penicyllamine
2-amino-3-methyl-3-sulfanyl-butanoic acid
DL-b-Mercaptovaline
3-Sulfanylvaline #
3-Mercapto-DL-valine
DL-DMC
.BETA.-THIOVALINE
PENICILLAMINE, DL-
NCIOpen2_000958
DL-Penicillamine (Standard)
SCHEMBL57527
.BETA.-MERCAPTOVALINE
MLS006011473
CHEMBL13239
SPECTRUM1500464
DTXSID7044687
HMS500P16
HMS1920F10
HMS2094G19
HMS3259K09
HMS3714E05
PENICILLAMINE DL-FORM [MI]
BCP24237
HY-W017457R
NSC22880
NSC44656
NSC81988
BBL013214
CCG-40247
s5962
STK249738
AKOS000121093
AKOS016843630
AB87081
CS-W018173
FP30177
HY-W017457
NC00476
2-Amino-3-mercapto-3-methylbutanoicacid
NCGC00018283-03
NCI60_001936
SMR000059161
SY045321
SY046568
SY049414
VS-03708
SBI-0051475.P003
DB-021813
DB-040965
NS00078845
NS00080914
P0025
butanoic acid, 2-amino-3-mercapto-3-methyl-
EN300-25364
AB00052067_10
AB00052067_11
AB00375988-03
(2RS)-2-amino-3-methyl-3-sulfanyl-butanoic acid
SR-05000001692
SR-05000001692-1
BRD-A16376407-213-01-1
Q27122242
Z203244248
L-(+)-2-Amino-3-mercapto-3-methylbutanoic acid |A,|A-Dimethyl-L-cysteine
beta,beta-Dimethyl-DL-cysteine, DL-2-Amino-3-mercapto-3-methylbutanoic acid