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O-Phospho-L-serine

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Identification
Molecular formula
C4H10NO6P
CAS number
407-41-0
IUPAC name
2-amino-3-phosphonooxy-butanoic acid
State
State

At room temperature, O-Phospho-L-serine is in a solid state, typically appearing as a crystalline powder.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
185.10g/mol
Molar mass
185.1270g/mol
Density
1.5008g/cm3
Appearence

O-Phospho-L-serine is typically a white crystalline solid. It may appear as a powder or granular form in laboratory settings.

Comment on solubility

Solubility of 2-amino-3-phosphonooxy-butanoic acid

2-amino-3-phosphonooxy-butanoic acid (C4H10NO6P) is a compound that exhibits interesting solubility characteristics. Generally, its solubility can be influenced by several factors:

  • Polarity: This compound contains both amino and phosphono functional groups, which contribute to its polar nature, enhancing its solubility in polar solvents such as water.
  • pH Dependence: The solubility may vary with pH changes, as the functional groups can be ionized, affecting the compound's overall solubility.
  • Temperature: Like many substances, an increase in temperature typically aids in solubilizing compounds; thus, higher temperatures may increase the solubility of this amino acid derivative.

In summary, due to its polar characteristics and functional groups, 2-amino-3-phosphonooxy-butanoic acid is generally expected to be soluble in water. However, as with many compounds, specific solubility can vary based on the solvent, temperature, and pH conditions. As such, one must always consider these factors when assessing solubility and its practical applications.

Interesting facts

Interesting Facts about 2-Amino-3-phosphonooxy-butanoic acid

2-Amino-3-phosphonooxy-butanoic acid, often referred to as APB, is an intriguing compound that holds significant relevance in both biological research and potential therapeutic applications. Here are some noteworthy points about this fascinating molecule:

  • Biochemical Significance: APB is recognized for its role as an agonist of the metabotropic glutamate receptors. This makes it a crucial compound for understanding synaptic transmission and neural plasticity.
  • Potential Therapeutic Applications: Due to its interactions with the brain's receptor systems, APB has been investigated for its potential in treating neurodegenerative diseases, mood disorders, and other neurological conditions.
  • Synthetic Pathways: The synthesis of APB can involve several innovative organic chemistry techniques. Understanding these pathways can provide insights into creating analogs with enhanced efficacy or selective actions.
  • Research in Neurobiology: Ongoing studies are exploring how APB influences neuronal calcium signaling, which can affect learning and memory processes. These studies contribute to our knowledge of the molecular basis of cognition.
  • Versatile Structure: The compound features a unique combination of amino acids and phosphonate groups. This unique structure allows it to engage in various biochemical interactions, making it a subject of interest for medicinal chemists.

As researchers continue to explore the functionalities of 2-amino-3-phosphonooxy-butanoic acid, it is clear that its contributions to science and medicine may open new pathways for therapeutic innovations. In the words of a prominent researcher in the field, "Understanding compounds like APB is essential to deciphering the complex chemistry of life itself."


Synonyms
O-Phospho-DL-threonine
27530-80-9
O-phosphonothreonine
2-amino-3-phosphonooxybutanoic acid
dl-O-Phosphothreonine
DL-Threonine phosphate
DL-Threonine dihydrogen phosphate
H-Thr(POH)-OH
NSC89296
EINECS 248-512-5
DL-Threonine, dihydrogen phosphate (ester)
CHEMBL369507
DTXSID10912145
NSC 89296
phosphothreonin
NSC-89296
(S)-2-Amino-3-hydroxybutanoic acid 3-phosphate
H-Thr(PO)-OH
Threonine, dihydrogen phosphate (ester), DL-
bmse000631
DL-2-Amino-3-hydroxybutanoic acid 3-phosphate
SCHEMBL13308410
CHEBI:190018
DTXCID301001959
2-Amino-3-phosphonooxy-butyric acid
BDBM50162817
AKOS015856719
HY-W142107
DB-040979
CS-0201891
NS00045165
P0255
248-512-5