Skip to main content

2-Amino-3,4,6-trichlorophenol

ADVERTISEMENT
Identification
Molecular formula
C6H4Cl3NO
CAS number
2735-52-2
IUPAC name
2-amino-3,4,6-trichloro-phenol
State
State

At room temperature, 2-Amino-3,4,6-trichlorophenol is usually found in a solid state, taking the form of a crystalline powder.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
455.00
Boiling point (Kelvin)
728.15
General information
Molecular weight
210.46g/mol
Molar mass
210.4790g/mol
Density
1.7980g/cm3
Appearence

2-Amino-3,4,6-trichlorophenol typically appears as an off-white to light brown crystalline powder. It may have a slight odor, characteristic of chlorinated phenols.

Comment on solubility

Solubility of 2-amino-3,4,6-trichloro-phenol

The solubility of 2-amino-3,4,6-trichloro-phenol, often referred to as Triclosan or a related derivative, can be characterized by several key points:

  • Polarity: The presence of multiple chlorine substituents and an amino group contributes to its overall polarity, significantly influencing its interactions with solvents.
  • Aqueous Solubility: Generally, 2-amino-3,4,6-trichloro-phenol exhibits low solubility in water owing to its hydrophobic chlorinated aromatic moiety, which limits its ability to dissolve in polar solvents.
  • Organic Solvents: It tends to be more soluble in organic solvents such as ethanol, methanol, and acetone, where the non-polar regions can better stabilize the compound.
  • Temperature Effects: Like many organic compounds, its solubility can increase with temperature, facilitating better interaction with solvents.
  • pH Influence: The solubility may also depend on the pH of the solution, particularly due to the protonation state of the amino group in varying pH conditions.

In summary, while 2-amino-3,4,6-trichloro-phenol is slightly soluble in aqueous solutions, its higher solubility in organic solvents makes it suitable for various applications where organic medium is preferred. The balance of hydrophilic and hydrophobic characteristics plays a vital role in its solubility profile.

Interesting facts

Interesting Facts About 2-amino-3,4,6-trichloro-phenol

2-amino-3,4,6-trichloro-phenol is a fascinating compound known for its unique chemical properties and applications. Here are several noteworthy points about this compound:

  • Structure and Function: This compound contains three chlorine atoms attached to a phenol ring along with an amino group. Its structure contributes to its potentially antioxidative and biocidal properties.
  • Applications in Science: Often used in various industrial and research applications, 2-amino-3,4,6-trichloro-phenol serves as a precursor in dye manufacturing and as an intermediate in the synthesis of more complex organic compounds.
  • Public Health Impact: As it has biocidal properties, this compound has been studied for its functionality in disinfection. However, it is also crucial to handle it with caution due to the associated health and environmental risks.
  • Regulatory Attention: Due to its chlorinated structure, 2-amino-3,4,6-trichloro-phenol is subject to rigorous regulatory scrutiny as there are concerns over its potential toxicity and environmental persistence.
  • Research Potential: Ongoing studies are assessing the effectiveness of this compound in combating certain pathogens, illustrating how substances with historical uses can find new relevance in modern science.

In summary, 2-amino-3,4,6-trichloro-phenol serves as a prime example of a compound whose chemical properties open avenues for further research while also demanding careful consideration of its safe usage.

Synonyms
2-AMINO-3,4,6-TRICHLOROPHENOL
6358-15-2
EINECS 228-763-7
Phenol, 2-amino-3,4,6-trichloro-
DTXSID80979801
NSC 7536
DTXCID701407086
3,4,6-TRICHLORO-2-AMINOPHENOL
2-HYDROXY-3,5,6-TRICHLOROANILINE
228-763-7
NSC7536
2-Amino-3,6-trichlorophenol
CHEMBL10513
SCHEMBL3319242
QQDKXJSYZGJGKJ-UHFFFAOYSA-N
GAA35815
NSC-7536
AKOS011655264
NS00043872
EN300-119075
G53610