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2-Amino-4-chlorothiophenol

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Identification
Molecular formula
C6H6ClNS
CAS number
137-17-7
IUPAC name
2-amino-4-chloro-benzenethiol
State
State

2-Amino-4-chlorothiophenol is typically solid at room temperature.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
159.64g/mol
Molar mass
159.6400g/mol
Density
1.3895g/cm3
Appearence

2-Amino-4-chlorothiophenol typically appears as a light yellow to yellow crystalline solid. It is known to have a distinct odor that is characteristic of thiophenol derivatives.

Comment on solubility

Solubility of 2-amino-4-chloro-benzenethiol

2-amino-4-chloro-benzenethiol, commonly referred to as a thiol compound, exhibits interesting solubility characteristics in various solvents. Its solubility is influenced by both its polar and nonpolar groups. Here are some key points to consider:

  • Solvent polarity: The polar amine and thiol functional groups in its structure contribute to its solubility in polar solvents such as water and ethanol.
  • Hydrogen bonding: The ability of 2-amino-4-chloro-benzenethiol to form hydrogen bonds enhances its solubility in aqueous solutions, making it more soluble compared to many non-polar compounds.
  • Organic solvents: The compound shows moderate solubility in organic solvents, particularly in those that can stabilize the polar characteristics, like dimethyl sulfoxide (DMSO) and acetone.

In contrast, solubility can be restricted in highly nonpolar solvents, due to the limited interaction with the solvent molecules. Therefore, understanding the solubility of 2-amino-4-chloro-benzenethiol is crucial for its application in various chemical processes and reactions.

In summary, the balance between its polar functional groups and the overall molecular structure determines the solubility behavior of 2-amino-4-chloro-benzenethiol across different solvents.

Interesting facts

Interesting Facts About 2-Amino-4-Chloro-Benzenethiol

2-Amino-4-chloro-benzenethiol, also known as p-chloroaniline thiol, is a fascinating compound with various applications in chemistry and industry. Here are some intriguing aspects of this compound:

  • Structure: The compound features a benzene ring substituted with an amino group and a chloro group, along with a thiol (-SH) functional group. This unique combination of functional groups offers interesting chemical properties, including reactivity and potential coordination capabilities.
  • Applications: 2-amino-4-chloro-benzenethiol is utilized in:
    • Dyes and pigments: It's key in the synthesis of various organic pigments.
    • Pharmaceuticals: It serves as an intermediate in the production of several bioactive compounds, contributing to medicinal chemistry.
    • Analytical chemistry: This compound is useful in detecting heavy metals due to its ability to form stable complexes.
  • Toxicity: Awareness of its toxicity is essential as it can pose health risks. 2-amino-4-chloro-benzenethiol should be handled with care in the laboratory due to its potential harmful effects if ingested or inhaled.
  • Isomerism: The presence of the amino and chloro groups provides opportunities for exploring stereoisomerism, and this could lead to the study of compound behavior in different environments.
  • Research Potential: Studies have been conducted to explore its properties as a potential bioregulator in plant systems, showcasing its utility beyond traditional applications.

As a compound that intersects various fields, 2-amino-4-chloro-benzenethiol exemplifies the importance of structural components in determining chemical reactivity and application. Emphasizing its educational value, studying this compound can deepen one's understanding of organic synthesis and the complexities of functional groups.

Synonyms
2-Amino-4-chlorobenzenethiol
1004-00-8
Benzenethiol, 2-amino-4-chloro-
DTXSID00143244
DTXCID4065735
2-Amino-4-chlorothiophenol
2-amino-4-chlorobenzene-1-thiol
2-amino-4-chloro-benzenethiol
2-Amino-4-chlorobenzenethiol (>85%)
NSC6957
5-Chloro-2-mercaptoaniline
4-Chloro-2-aminothiophenol
MFCD00792528
4-chloro-o-aminothiophenol
2-Amino-4-chloro thiophenol
4-Chloro-2-aminobenzenethiol
5-Chloro-2-mercaptoaniline-
SCHEMBL485284
Aniline, 5-chloro-2-mercapto-
2-azanyl-4-chloranyl-benzenethiol
STR07514
2-Amino-4-chlorophenyl hydrosulfide
2-Amino-4-chlorobenzenethiol, 96%
BBL100251
STL553820
AKOS000298976
CS-W016174
PS-3202
SB76303
AC-11158
DB-005932
A1625
EN300-21735
F10521
A800195
F8889-1244
Z108565176
2-Amino-4-chlorothiophenol; 2-Amino-4-cholorobenzenethiol; 4-Chloro-2-aminothiophenol; 5-Chloro-2-mercaptoaniline;