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2-Amino-4-methylphenol

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Identification
Molecular formula
C7H9NO
CAS number
95-84-1
IUPAC name
2-amino-4-methyl-phenol
State
State

At room temperature, 2-Amino-4-methylphenol is in a solid state. It typically presents as a crystalline powder, which is characteristic of many small organic compounds.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
123.16g/mol
Molar mass
123.1580g/mol
Density
1.1799g/cm3
Appearence

2-Amino-4-methylphenol appears as a light brown crystalline solid. It is commonly used in various applications, notably in the formulation of dyes and hair coloring products. The compound's appearance may vary slightly depending on its purity and the presence of any impurities.

Comment on solubility

Solubility of 2-amino-4-methyl-phenol

2-amino-4-methyl-phenol, with the chemical formula C7H9NO, exhibits interesting solubility characteristics, which can be influenced by various factors. Below are some key points regarding its solubility:

  • Solvent Compatibility: This compound is generally soluble in organic solvents, such as ethanol and acetone, due to its aromatic structure and hydrophobic characteristics.
  • Water Solubility: 2-amino-4-methyl-phenol shows limited solubility in water, primarily because of the relatively nonpolar nature of its phenolic group. However, it may form hydrogen bonds with water, enhancing its solubility slightly under certain conditions.
  • pH Effects: The solubility of this compound can be affected by the pH of the solution. At lower pH levels, the amine group may become protonated, potentially increasing its solubility in aqueous solutions.

To summarize, the solubility of 2-amino-4-methyl-phenol is characterized by:

  1. Higher solubility in organic solvents.
  2. Limited water solubility with potential pH-dependent behavior.
  3. Influence of molecular structure on solvation properties.

Understanding these solubility properties is essential for applications in pharmaceuticals and material sciences, where solubility impacts reactivity, bioavailability, and overall effectiveness.

Interesting facts

Interesting Facts About 2-Amino-4-methyl-phenol

2-Amino-4-methyl-phenol, commonly known as p-cresidine, is a fascinating compound with several noteworthy characteristics and applications. Below are some interesting facts:

  • Structure and Function: This compound features an amino group and a methyl group attached to a phenolic ring. Its unique structure contributes to its reactivity and utility in various chemical reactions.
  • Applications: 2-Amino-4-methyl-phenol is primarily used in the manufacturing of azo dyes. The presence of the amino group allows it to participate in coupling reactions, which are essential in the formation of these dyes, leading to vibrant and diverse color palettes.
  • Biological Activity: Research has shown that derivatives of 2-amino-4-methyl-phenol exhibit potential biological activity. For example, certain derivatives have been assessed for their antibacterial and antifungal properties, highlighting their significance in medicinal chemistry.
  • Safety Considerations: While working with this compound, it's important to note that it may be hazardous. Proper safety protocols should be followed, including the use of personal protective equipment (PPE) and working in well-ventilated areas, as it can potentially cause skin irritation or other adverse effects.
  • Historical Significance: The study of compounds like 2-amino-4-methyl-phenol has contributed significantly to the field of synthetic organic chemistry, illustrating the importance of structure-activity relationships and paving the way for the development of new materials and pharmaceuticals.

As a chemistry student or a researcher, exploring compounds like 2-amino-4-methyl-phenol not only deepens your understanding of organic compounds but also highlights the intricate connections between structure, properties, and applications in everyday life.

Synonyms
2-Amino-4-methylphenol
95-84-1
2-Amino-p-cresol
2-Hydroxy-5-methylaniline
3-Amino-4-hydroxytoluene
6-Hydroxy-m-toluidine
Phenol, 2-amino-4-methyl-
4-Methyl-2-aminophenol
5-Methyl-2-hydroxyaniline
p-Cresol, 2-amino-
CCRIS 4581
2-amino-4-methyl-phenol
2-Amino-4-methyl phenol
m-Amino-p-cresol
EINECS 202-457-3
NSC 60737
4-METHYL-O-AMINOPHENOL
BRN 0606494
9ZV2574SER
DTXSID4024488
1-amino-2-hydroxy-5-methylbenzene
NSC-7630
NSC-60737
2A4MP
UNII-9ZV2574SER
(2-HYDROXY-5-METHYLPHENYL)AMINE
1-HYDROXY-2-AMINO-4-METHYLBENZENE
DTXCID804488
4-13-00-01712 (Beilstein Handbook Reference)
2-Amino-4-cresol
2Aminopcresol
pCresol, 2amino
6Hydroxymtoluidine
4Methyl2aminophenol
MFCD00007699
3Amino4hydroxytoluene
2Hydroxy5methylaniline
5Methyl2hydroxyaniline
Phenol, 2amino4methyl
pCresol, 2amino (8CI)
1Amino2hydroxy5methylbenzene
1Hydroxy2amino4methylbenzene
MLS002454361
p-Cresol, 2-amino-(8CI)
SCHEMBL104502
CHEMBL224282
2-Amino-4-methylphenol, 97%
CHEBI:39713
NSC7630
HMS3039M15
KUC106693N
NSC60737
Tox21_200692
BBL001485
STL115535
AKOS000345514
CS-W004057
DB04533
FA16097
PS-5548
CAS-95-84-1
NCGC00091594-01
NCGC00091594-02
NCGC00091594-03
NCGC00258246-01
2AC
AC-10115
KSC-11-207-3
PD006024
SMR001371986
A0330
NS00015128
EN300-50872
D70667
Q27095299
F0001-2282
Z394651082
2-Amino-p-cresol;3-Amino-4-hydroxytoluene;2-Hydroxy-5-methylaniline