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2-Amino-4-methylsulfonylphenol

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Identification
Molecular formula
C7H9NO3S
CAS number
2213-63-0
IUPAC name
2-amino-4-methylsulfonyl-phenol
State
State

At room temperature, 2-amino-4-methylsulfonylphenol is typically in a solid state.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
185.21g/mol
Molar mass
185.2140g/mol
Density
1.5300g/cm3
Appearence

This compound is typically found as a white to off-white crystalline solid. It may exhibit slight hygroscopic properties.

Comment on solubility

Solubility of 2-amino-4-methylsulfonyl-phenol

The solubility characteristics of 2-amino-4-methylsulfonyl-phenol can provide invaluable insights into its behavior in various environments. This compound has unique functional groups that influence its interaction with solvents, particularly water.

Key Factors Affecting Solubility:

  • Polarity: The presence of the sulfonyl group (-SO2-), combined with the amino group (-NH2), enhances overall polarity, allowing it to interact favorably with polar solvents.
  • Hydrogen Bonding: The amino group can participate in hydrogen bonding, which further aids in solubility in water.
  • pH Dependence: The solubility may vary depending on the pH of the solution; at different pH levels, the ionization of the amino group can affect how well the compound dissolves.

As a result, 2-amino-4-methylsulfonyl-phenol is generally expected to be soluble in polar solvents such as water, but its solubility might decrease in non-polar solvents. Such characteristics are important to consider in applications like pharmaceuticals, where bioavailability greatly depends on solubility.

In summary, the solubility of 2-amino-4-methylsulfonyl-phenol highlights the interplay between molecular structure and solvent interactions, showcasing how chemical functionality dictates behavior in different environments.

Interesting facts

Interesting Facts about 2-Amino-4-methylsulfonyl-phenol

2-Amino-4-methylsulfonyl-phenol is a fascinating compound that holds significance in various fields of chemistry and biotechnology. Here are some remarkable aspects of this compound:

  • Chemical Structure: This compound features an amino group and a methylsulfonyl group, which contribute to its unique properties. The presence of these functional groups can influence the solubility and reactivity of the molecule.
  • Pharmaceutical Applications: Compounds like 2-amino-4-methylsulfonyl-phenol often serve as building blocks in the synthesis of pharmaceuticals. The sulfonamide group is known for its role in antibiotic and anti-inflammatory medications.
  • Biological Importance: Research has shown that sulfonamide derivatives exhibit a range of biological activities, including antimicrobial and anti-cancer properties, making them of significant interest in medicinal chemistry.
  • Stability: Due to its structural characteristics, 2-amino-4-methylsulfonyl-phenol demonstrates considerable stability under various conditions, which is crucial for its applicability in laboratory and industrial settings.
  • Synthesis: The synthesis of this compound can involve several methods, including the reaction of sulfonyl chlorides with phenolic compounds, highlighting the versatility of synthetic organic chemistry.
  • Research Potential: Ongoing research into the potential applications of 2-amino-4-methylsulfonyl-phenol continues to reveal new and exciting possibilities, particularly in the fields of drug design and development.

In summary, 2-amino-4-methylsulfonyl-phenol is not just an ordinary chemical compound; it represents a confluence of chemical ingenuity and the quest for new therapeutic agents. As Marie Curie once said, “Nothing in life is to be feared, it is only to be understood.” This compound embodies that spirit, opening doors for further understanding and exploration in the fascinating world of chemistry.

Synonyms
98-30-6
2-AMINO-4-(METHYLSULFONYL)PHENOL
4-Methylsulfonyl-2-aminophenol
3-Amino-4-hydroxyphenyl Methyl Sulfone
2-Amino-4-(methylsulphonyl)phenol
CCRIS 5961
2-amino-4-methylsulfonylphenol
Phenol, 2-amino-4-(methylsulfonyl)-
2-amino-4-methanesulfonylphenol
EINECS 202-654-4
DTXSID8024490
EN300-78665
2-amino-4(methylsulfonyl)phenol
MFCD00719450
SVT24HP8UU
Oprea1_483830
Oprea1_545644
SCHEMBL634380
DTXCID904490
2-Hydroxy-5-methylsulfonylaniline
BDBM626212
2-Hydroxy-5-(methylsulfonyl)aniline
Amino-4-(methylsulfonyl)phenol, 2-
AKOS003614439
AC-4580
PS-5643
BP-13390
A2198
NS00040529
D88514
Z57187730
202-654-4