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2-Amino-4-nitrobenzoic acid

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Identification
Molecular formula
C7H6N2O4
CAS number
610-81-1
IUPAC name
2-amino-4-nitro-benzoic acid
State
State

At room temperature, 2-Amino-4-nitrobenzoic acid is a solid. It is typically handled as a powder or crystalline solid, depending on the context.

Melting point (Celsius)
263.00
Melting point (Kelvin)
536.15
Boiling point (Celsius)
452.15
Boiling point (Kelvin)
725.30
General information
Molecular weight
182.14g/mol
Molar mass
182.1450g/mol
Density
1.5697g/cm3
Appearence

2-Amino-4-nitrobenzoic acid appears as a yellow crystalline solid. It can vary in hue from lighter to more intense yellow, depending on the purity and specific conditions in which it is encountered.

Comment on solubility

Solubility of 2-amino-4-nitro-benzoic acid

2-amino-4-nitro-benzoic acid, often referred to as p-aminonitrobenzoic acid, exhibits unique solubility properties that are influenced by its functional groups. This compound is known to be:

  • Slightly soluble in water, which can be attributed to the presence of both the amino group and the carboxylic acid group in its structure. These polar functional groups facilitate some degree of interaction with water molecules.
  • More soluble in organic solvents such as ethanol and acetone, highlighting its hydrophobic characteristics when compared to its polar interactions.

Here are some notable points regarding its solubility:

  • The amino group can form hydrogen bonds with water, enhancing its solubility.
  • The nitro group, while polar, also imparts stability to the molecule, affecting its solubility dynamics.
  • The overall structure can lead to variations in solubility based on pH, particularly when it ionizes in different conditions.

In conclusion, while 2-amino-4-nitro-benzoic acid is only moderately soluble in water, its solubility profile in organic solvents makes it a versatile compound for various applications.

Interesting facts

Interesting Facts About 2-Amino-4-Nitrobenzoic Acid

2-Amino-4-nitrobenzoic acid, also known as p-aminonitrobenzoic acid, is a fascinating compound that belongs to the category of amino acids and is notable for its diverse applications in both pharmaceuticals and materials science.

Key Highlights:

  • Pharmaceutical Applications: This compound has garnered attention in the field of drug development due to its role in synthesizing various pharmaceuticals. It acts as an intermediate in the production of important medications.
  • Colorimetric Reagent: 2-Amino-4-nitrobenzoic acid is often utilized in colorimetric assays, particularly in determining the concentration of amino acids and proteins. Its ability to form colored complexes enhances the sensitivity of these assays.
  • Structural Insights: The unique placement of the amino and nitro groups on the benzene ring provides intriguing insights into the compound's reactivity and interaction with other molecules, making it a subject of study in organic chemistry.
  • Environmental Considerations: As a nitroaromatic compound, it is important to consider the environmental impact and potential toxicity when handling and disposing of substances like 2-amino-4-nitrobenzoic acid.

This compound exemplifies the versatility and significance of nitro-substituted benzoic acids in both natural and synthetic contexts. Its study not only broadens our understanding of organic compounds but also leads to innovations that contribute to various scientific fields.

Synonyms
2-Amino-4-nitrobenzoic acid
619-17-0
4-NITROANTHRANILIC ACID
Benzoic acid, 2-amino-4-nitro-
Anthranilic acid, 4-nitro-
NCI-C01945
4-nitro-2-aminobenzoic acid
CCRIS 441
HSDB 4114
NSC 7789
EINECS 210-583-5
BRN 0785071
DTXSID8020963
CHEBI:75335
NSC-7789
D7402082SS
DTXCID00963
2-CARBOXY-5-NITROANILINE
4-14-00-01087 (Beilstein Handbook Reference)
4-NITROANTHRANILIC ACID [HSDB]
2Amino4nitrobenzoic acid
Anthranilic acid, 4nitro
Benzoic acid, 2amino4nitro
210-583-5
inchi=1/c7h6n2o4/c8-6-3-4(9(12)13)1-2-5(6)7(10)11/h1-3h,8h2,(h,10,11
2-amino-4-nitro-benzoic acid
MFCD00007262
2-Amino-4-nitrobenzoicacid
CAS-619-17-0
UNII-D7402082SS
4-nitroanthranilate
p-Nitroanthranilic acid
4-nitrroanthranilic acid
WLN: WNR C1 DVQ
SCHEMBL436780
2-Aminobenzoic acid, 4-nitro-
CHEMBL1603870
NSC7789
Tox21_201312
Tox21_302942
BBL034649
STK661381
AKOS001044179
AC-2570
CS-W002027
PS-6128
NCGC00091675-01
NCGC00091675-02
NCGC00091675-03
NCGC00091675-04
NCGC00256461-01
NCGC00258864-01
BP-10411
SY002165
DB-005940
EU-0086006
N0522
NS00034843
EN300-17254
4-Nitroanthranilic acid, technical grade, 90%
AB01322613-02
AN-584/40848509
SR-01000532452
SR-01000532452-1
Q27145223
Z56899198