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O-Phospho-L-serine

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Identification
Molecular formula
C4H10NO6P
CAS number
407-41-0
IUPAC name
2-amino-4-phosphonooxy-butanoic acid
State
State
At room temperature, O-Phospho-L-serine is typically found in solid state.
Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
378.15
Boiling point (Kelvin)
651.15
General information
Molecular weight
185.11g/mol
Molar mass
185.1290g/mol
Density
2.0920g/cm3
Appearence

O-Phospho-L-serine usually appears as a white crystalline powder. It may also be available as a fine granular solid.

Comment on solubility

Solubility of 2-amino-4-phosphonooxy-butanoic acid

2-amino-4-phosphonooxy-butanoic acid (C4H10NO6P) is a compound notable for its intriguing solubility properties. Here are some key points regarding its solubility:

  • Water Solubility: This compound exhibits good solubility in water due to the presence of multiple polar functional groups, such as amino and phosphono groups. These groups engage in hydrogen bonding with water molecules, facilitating dissolution.
  • Organic Solvents: Its solubility in organic solvents tends to be limited. Compounds with high polarity often struggle to dissolve in nonpolar solvents, which is characteristic for 2-amino-4-phosphonooxy-butanoic acid.
  • pH Dependence: The solubility may also vary with pH; under acidic or basic conditions, the ionization state of the functional groups can alter solubility behavior significantly.
  • Temperature Influence: Generally, an increase in temperature can enhance solubility, potentially allowing for greater dissolution of the compound in aqueous solutions.

In summary, 2-amino-4-phosphonooxy-butanoic acid is soluble in water, making it readily available for biological and chemical interactions, while its solubility in organic solvents remains minimal. Understanding these solubility characteristics can help in predicting the behavior of this compound in various environments.

Interesting facts

Interesting Facts about 2-amino-4-phosphonooxy-butanoic acid

2-amino-4-phosphonooxy-butanoic acid, often abbreviated as APBA, is a fascinating compound that brings together important aspects of biochemistry and pharmacology. Here are some engaging insights:

  • Biological Significance: This compound is a derivative of the amino acid aspartic acid and plays a crucial role in neurotransmission and neuronal signaling.
  • Potential Therapeutic Uses: APBA is under investigation for its potential role in neurological disorders. Its modulation of excitatory neurotransmitter receptors could offer new treatment avenues.
  • Structure-Activity Relationship: The phosphonooxy group in APBA is key to its interactions with biological molecules, making it a topic of great interest in medicinal chemistry.
  • Synthesis Challenges: The synthesis of APBA often involves complex chemical reactions that require precise control of conditions to achieve desired products and yields.

As quotes from renowned scientists often remind us, “The beauty of chemistry is the infinite complexity of interactions at a molecular level.”
2-amino-4-phosphonooxy-butanoic acid exemplifies this complexity, bridging various fields and expanding our understanding of molecular interactions.

Ultimately, the study of this compound not only enhances our understanding of fundamental biological processes but also drives the quest for innovative therapeutic solutions. Researchers continue to explore its myriad applications, highlighting the ongoing importance of such compounds in advancing both science and medicine.

Synonyms
O-Phosphorylhomoserine
O-phosphorylhomoserines
CHEBI:21969
2-amino-4-phosphonooxybutanoic acid
O-phospho-dl-homoserine
SCHEMBL1332612
C05702